Signal Transducing Molecules and Colorectal Cancer - Kashmir Scenario | The Genetic Alterations of the Signal Transducing Molecules and their role in the development and progression of Colorectal Cancer in Kashmir Valley

Aga Syed Sameer

ISBN 10: 384336656X / ISBN 13: 9783843366564

Published by LAP LAMBERT Academic Publishing, 2010

About this Item

Signal Transducing Molecules and Colorectal Cancer - Kashmir Scenario | The Genetic Alterations of the Signal Transducing Molecules and their role in the development and progression of Colorectal Cancer in Kashmir Valley | Aga Syed Sameer | Taschenbuch | 232 S. | Englisch | 2010 | LAP LAMBERT Academic Publishing | EAN 9783843366564 | Verantwortliche Person für die EU: BoD - Books on Demand, In de Tarpen 42, 22848 Norderstedt, info[at]bod[dot]de | Anbieter: preigu.

Seller Inventory # 107232888

Bibliographic Details

• Title: Signal Transducing Molecules and Colorectal Cancer - Kashmir Scenario | The Genetic Alterations of the Signal Transducing Molecules and their role in the development and progression of Colorectal Cancer in Kashmir Valley
• Publisher: LAP LAMBERT Academic Publishing
• Publication Date: 2010
• Language: English
• ISBN 10: 384336656X
• ISBN 13: 9783843366564
• Binding: Taschenbuch
• Condition: Neu
• Dimensions: 220W x 150H x 14D millimeters 220 millimeters width by 150 millimeters height by 14 millimeters depth
• Weight: 364 grams
• Seller catalogs:
  • Bücher

About this title

Synopsis

The underlying theme of this doctoral thesis was ? To evaluate the role of genetic aberrations in different signal transducing molecules of important signal transduction pathways that are involved in the development and progression of CRC in Kashmiri population. ? To assess the possible association between the genetic aberrations of the signal transducing molecules and various life style factors that are likely to lead to the development and progression of colorectal cancer. ? To observe the significance of multistep model of CRC carcinogenesis in explaining the CRC carcinogenesis in our Kashmiri population. After assessing the various signal transducing molecules for genetic aberrations we found that the multi-step model of CRC carcinogenesis holds well in explaining the CRC tumorigenesis in our Kashmiri population but with a slight difference in manner and frequency of genetic aberrations of key tumor suppressor genes and oncogenes.

About the Author

The author is presently working as a Senior Research Scholar in Department of Immunology & Molecular Medicine in SKIMS, Kashmir in pursuance of his doctoral degree on molecular pathogenesis of CRC in Kashmir Valley. He has completed his Master?s Degree in Biochemistry from Kashmir University. He has also qualified the prestigious CSIR-JRF.