Ancien livre de biblioth�que avec �quipements. Edition 2011. Ammareal reverse jusqu'� 15% du prix net de cet article � des organisations caritatives. ENGLISH DESCRIPTION Book Condition: Used, Very good. Former library book. Edition 2011. Ammareal gives back up to 15% of this item's net price to charity organizations.

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Bibliographic Details

Title: Signposts to Chiral Drugs: Organic Synthesis in Action
Publisher: Springer
Publication Date: 2011
Language: English
ISBN 10: 3034801246
ISBN 13: 9783034801249
Binding: Hardcover
Condition: Tr�s bon

About this title

Synopsis

Highlighting 15 selected chiral structures, which represent candidate or marketed drugs, and their chemical syntheses, the authors acquaint the reader with the fascinating achievements of synthetic and medicinal chemistry.

The book starts with an introduction treating the discovery and development of a new drug entity. Each of the 15 subsequent chapters presents one of the target structures and begins with a description of its biological profile as well as any known molecular mechanisms of action, underlining the importance of its structural and stereochemical features. This section is followed by detailed discussions of synthetic approaches to the chiral target structure, highlighting creative ideas, the scaling-up of laboratory methods and their replacement by efficient modern technologies for large-scale production. Nearly 60 synthetic reactions, most of them stereoselective, catalytic or biocatalytic, as well as chiral separating methodologies are included in the book.

Vitomir Sunjic and Michael J. Parnham provide an invaluable source of information for scientists in academia and the pharmaceutical industry who are actively engaged in the interdisciplinary development of new drugs, as well as for advanced students in chemistry and related fields.

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English below. Ammareal est une librairie professionnelle sp�cialis�e dans le livre d?occasion. Nous exp�dions partout dans le monde. Nous avons plus de 250 000 ouvrages en stock dont un grand nombre de livres techniques et acad�miques. Nous reversons jusqu?� 15% du prix de vente de chaque livre � des organisations caritatives, des biblioth�ques et des associations luttant contre l?illettrisme. Ce que nous ne vendons pas nous le donnons, ce que nous ne donnons pas nous le recyclons. Ammareal is a professional bookseller speciliazed in used books. We ship worldwide. We have more than 250 000 books in stock, including a large number of technical and university-level books. We give back up to 15% of the price of each book to charities, libraries and organizations fighting in favor of literacy. What we do not sell, we give, what we do not give we recycle.

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