This nonfiction work surveys known bases and those of unknown constitution, tracing their discovery, properties, and the methods used to isolate and study them. The book blends historical context with chemical detail to illuminate a key area of biochemistry.

Learn how bases like spermine and guanidine were characterized, including their salts and crystalline forms.
See how researchers approached bases from urine, muscle, and fermentation products, and the challenges they faced.
Explore the methods scientists used to isolate and identify active substances in complex mixtures.
Understand the evolution of ideas about bases of unknown constitution and their physiological relevance.

Ideal for readers interested in the history and methods of early biochemistry, and for those seeking a clear window into how simple bases were investigated and understood in this era.

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