Solid-Phase Extraction: Principles and Practice

Divided into three main parts, the book begins with a clearexplanation of basic SPE conceptsincluding theory, chemistry, andmechanisms of interaction as well as methods development,troubleshooting, and optimization. The next section presents anin-depth look at SPE applications, with separate chapters devotedto clinical, environmental, and natural product chemistry. Numerousexamples drawn from each of these three areas illustrate SPE inaction in the real world, successfully bridging the gap betweenprinciples and practice.

The final section of this book discusses the latest SPEtechnology, with detailed coverage of the automation process,solid-phase extraction disks, and innovations such as solid-phasemicroextraction and small-volume solid-phase extraction. Suggestedreading and references are included throughout, providing a usefulspringboard for further research and study.

Whether you are new to SPE or are looking to keep abreast of thenewest developments in SPE methods and uses, Solid-Phase Extractiongives you instant access to the information you needan essentialcompanion for chemists of all types who use SPE in their work.

Complete coverage of SPE concepts and applicationsat yourfingertips Solid-Phase Extraction (SPE) equips chemists in anyfield with an incomparable one-stop source of up-to-dateinformation on SPE. With sections devoted to fundamentalprinciples, applications, and new technology, it is bothcomprehensive and easy to use the ideal working reference on thisimportant subject.
* Presents a straightforward examination of SPE theory, methodsdevelopment, chemistry, and mechanisms of interaction
* Provides detailed coverage of SPE applications in clinical,environmental, and natural product chemistry
* Features practical examples illustrating a range of real-worldSPE uses
* Prepares chemists to make informed decisions on sorbentselection
* Covers the latest SPE technology, with valuable insights onautomation and new sample preparation methods
* Offers suggestions for further reading, Internet resources, andproduct guides

E. M. THURMAN is an organic geochemist at the U.S. GeologicalSurvey with twenty years of research experience in theenvironmental chemistry of water and soil, as well as extensiveexperience in sorption chromatography and XAD and SPE resintechnology. Dr. Thurman has published research papers on the theoryof XAD resins, applications of SPE in environmental chemistry, drugapplications of SPE, and isolation of natural products by SPE andion exchange. He is the coauthor of Immunochemical Technology forEnvironmental Applications, the coeditor of Herbicide Metabolitesin Surface Water and Groundwater, and has written over 80 journalarticles on environmental analytical chemistry.

M. S. MILLS is a research envi-ronmental chemist with ZenecaAgrochemicals at the Jealott's Hill Research Station, Bracknell,U.K. Dr. Mills was formerly employed by the U.S. Geological Surveyin Lawrence, Kansas, where her research interests includedexploring the mechanisms and applications of solid-phase extractionin environmental chemistry, investigating the organic geochemistryof naturally occurring aquatic foams, and the degradation andtransport of xenobiotics in the vadose zone. She has contributednumerous publications and oral presentations on these topics overthe past five years, and was cofounder and co-lecturer of theAmerican Chemical Society short course, "Solid-Phase Extraction inEnvironmental and Clinical Chemistry." Current research projectfoci include the degradation and transport of xenobiotics in thevadose zone using radiolabeled techniques and the degradation ofxenobiotics in the saturated zone.