Title: Source and Target of Inflammatory Mediators: v. 330 (NATO Science Series A: Life Sciences) [Hardcover] Catravas, John D.; etc.; Callow, A.D.; Ryan, U.S. and Simionescu, M.
Publisher: SAGE Publications Ltd
Publication Date: 2006
Language: English
ISBN 10: 1586030922
ISBN 13: 9781586030926
Binding: Hardcover
Condition: Fine

About this title

Synopsis

The June/July NATO Advanced Study Institute resulted in these 15 papers that explore the cellular biology of vascular endothelium. Specific topics include an immunotherapeutic approach for the treatment of low plasma HDL-Cholesterol, effect of hyperlipemia and hyperglycemia on the vascular endothelium, endothelium-based approaches to stroke therapy, expressional regulation and subcellular localization of the nitric oxide receptor soluble guanylyl cyclase, and pathophysiological consequences of complement-endothelial cell interaction. Annotation c. Book News, Inc., Portland, OR (booknews.com)

From the Back Cover

This is the seventh in a series of monographs on aspects of endothelial cell biology. All are derived from the proceedings of similarly titled NATO-sponsored Advanced Study Institutes. The book includes chapters on the clinical profile of important vascular diseases, such as pulmonary hypertension, atherosclerosis and stroke, as well as chapters in various underlying biological mechanisms. Present are in depth discussions on the role of endothelins, type 1, 2 and 3 nitric oxide synthases, guanyl cyclases, cadherins, pentraxins, various transcriptions factors regulating relevant gene activations, intracellular signaling molecules, thrombin and complement. Also discussed are regulatory processes, including apoptosis, hyperlipidemia and hyperglycemia, endothelial cell permeability, microvascular architecture, as well as exciting new advances in the management of atherosclerosis and stroke.

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