Spectroscopic Methods in Organic Chemistry

This book is an introductory text that describes the uses of the four spectroscopic methods: UV, IR, NMR and mass spectra in structure determination in organic chemistry. In addition to the material covered in the fourth edition there is extended coverage of 2-D NMR spectra, including the powerful techniques of TOCSY (total correlation spectroscopy) and [superscript 13]C-[superscript 1]H hetero-correlations, plus the introduction of ESI (electrospray ionization) and MALDI (matrix-assisted laser desorption). It is written for all scientists with an interest in the structure determination of organic molecules, and is an essential source of reference data.

Dudley Williams was an undergraduate at the University of Leeds (1955-1958), and obtained his PhD (1958-1961) there under the supervision of Professor Basil Lythgoe. Following postdoctoral research at Stanford University (1961-1964) with Professor Carl Djerassi, he followed an academic career in Cambridge, as a Fellow of Churchill College, and in the Department of Chemistry. His research involved developments in proton nuclear magnetic resonance and mass spectrometry, and, most famously, he and his co-workers elucidated the structure and mode of action of the clinically important antibiotic vancomycin.

Ian Fleming studied at Pembroke College, Cambridge, obtaining his PhD in 1962 in the University Chemical Laboratory supervised by Dr John Harley-Mason. Except for a postdoctoral year at Harvard (1963-1964) with Professor R. B. Woodward, and sabbatical visits to McGill University in Montreal (1972 And 1978), the University of Wisconsin in Madison (1980), and Harvard University (1990), he has spent his entire academic career in Cambridge. In research, he is best known for his work on the application of organosilicon chemistry to solving problems of regiocontrol and stereocontrol in organic synthesis.