The Sperm Cell: Production, Maturation, Fertilization, Regeneration, 2/E (Hb 2017)

This revised and updated second edition provides a comprehensive account of the human male gamete. Detailed overviews of human sperm production, maturation, and function - and how these processes affect and influence fertility, infertility, and assisted reproduction - are given. A wide range of new developments including proteomics, spermatogenesis, sperm-specific WW domain-binding proteins, Ca2+ signalling, DNA packaging, epididymis are explored, whilst a new chapter presents information gained from mouse genetics, highlighting how it informs male fertility research. The impact of environmental factors during pre-pubertal and pubertal stages of life is also investigated. Featuring engaging prose with chapters organized topographically, The Sperm Cell remains an essential resource for andrologists, clinical scientists, and laboratory personnel.

Christopher De Jonge is Director of the Andrology Program at the University of Minnesota Medical Center and Adjunct Professor in the Department of Urology at the University of Minnesota.

Christopher L. R. Barratt is Professor of Reproductive Medicine at the School of Medicine, University of Dundee, Ninewells Hospital, Dundee.