The growing interest in using combination drugs to treat various complex diseases has spawned the development of many novel statistical methodologies. The theoretical development, coupled with advances in statistical computing, makes it possible to apply these emerging statistical methods in in vitro and in vivo drug combination assessments. However, despite these advances, no book has served as a single source of information for statistical methods in drug combination research, nor has there been any guidance for experimental strategies.

Statistical Methods in Drug Combination Studies fills that gap, covering all aspects of drug combination research, from designing in vitro drug combination studies to analyzing clinical trial data. Featuring contributions from researchers in industry, academia, and regulatory agencies, this comprehensive reference:

Describes statistical models used to characterize dose–response patterns of monotherapies and evaluate the combination drug synergy

Offers guidance for estimating interaction indices and constructing their associated confidence intervals to assess drug interaction

Introduces a practical and innovative Bayesian approach to Phase I cancer trials, including actual trial examples to illustrate use

Examines strategies in the fixed-dose combination therapy clinical development via case studies stemming from regulatory reviews

Evaluates computational tools and software packages used to apply novel statistical methods in combination drug development

Statistical Methods in Drug Combination Studies provides researchers with a solid understanding of the available statistical methods and computational tools and how to apply them in drug combination studies. The book is equally useful for statisticians to become better equipped to deal with drug combination study design and analysis in their practice.

About the Author

Wei Zhao, Harry Yang

"About this title" may belong to another edition of this title.

Store Description

SuperBookDeals.com is your top source for finding new books at the absolute lowest prices, guaranteed ! We offer big discounts - everyday - on millions of titles in virtually any category, from Architecture to Zoology -- and everything in between. Discover great deals and super-savings, on professional books, text book titles, the newest computer guides, or your favorite fiction authors. You'll find it all - at HUGE SAVINGS - at SuperBookDeals. Browse through our complete online product catalog today. Serving customers around the world for years, we help thousands find just the books they're looking for -- at incredibly low, bargain prices.

Visit Seller's Storefront

Seller's business information

Expert Trading Limited
9220 Rumsey Road, Suite 101, Columbia, MD, 21045, U.S.A.

Sale & Shipping Terms

Terms of Sale

Company Name: GreatBookPrices
Legal Entity: Expert Trading, LLC
Address: 9220 Rumsey Road, Ste 101, Columbia MD 21046
Email address: CustomerService@SuperBookDeals.com
Phone number: 410-964-0026
consumer complaints can be addressed to address above
Registration #: 52-1713923
Authorized representative: Danielle Hainsey

Shipping Terms

Internal processing of your order will take about 1-2 business days. Please allow an additional 4-14 business days for Media Mail delivery. We have multiple ship-from locations - MD,IL,NJ,UK,IN,NV,TN & GA

Shipping rates within U.S.A.

Shipping rates within U.S.A.
Order quantity	8 to 14 business days	5 to 14 business days
First item	US$ 2.64	US$ 2.64

Delivery times are set by sellers and vary by carrier and location. Orders passing through Customs may face delays and buyers are responsible for any associated duties or fees. Sellers may contact you regarding additional charges to cover any increased costs to ship your items.