Structure, Activity, And Function Of Protein Methyltransferases

ISBN 10: 303654139X ISBN 13: 9783036541396

Published by Mdpi AG, 2022

Language: English

Condition: New Hardcover

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Bibliographic Details

Title

Structure, Activity, And Function Of Protein Methyltransferases

Publisher

Mdpi AG

Publication Date

2022

Language

English

ISBN 10

303654139X

ISBN 13

9783036541396

Binding

Hardcover

Condition

New

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About this title

Synopsis

This collection of review articles describes the structure, function and mechanism of individual protein methyltransferase enzymes including protein lysine methyltransferases, protein arginine methyltransferases, and also the less abundant protein histidine methyltransferases and protein N-terminal end methyltransferases. The topics covered in the individual reviews include structural aspects (domain architecture, homologs and paralogs, and structure), biochemical properties (mechanism, sequence specificity, product specificity, regulation, and histone and non-histone substrates), cellular features (subcellular localization, expression patterns, cellular roles and function, biological effects of substrate protein methylation, connection to cell signaling pathways, and connection to chromatin regulation) and their role in diseases. This review book is a useful resource for scientists working on protein methylation and protein methyltransferases and those interested in joining this emerging research field.

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