Structured Biological Modelling: A New Approach to Biophysical Cell Biology

Kraus, Michael; Wolf, Bernhard

ISBN 10: 0849347726 / ISBN 13: 9780849347726

Published by CRC Press, 1995

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Bibliographic Details

• Title: Structured Biological Modelling: A New Approach to Biophysical Cell Biology
• Publisher: CRC Press
• Publication Date: 1995
• Language: English
• ISBN 10: 0849347726
• ISBN 13: 9780849347726
• Binding: Hardcover
• Condition: New

About this title

Synopsis

Structured Biological Modelling presents a straightforward introduction for computer-aided analysis, mathematical modelling, and simulation of cell biological systems. This unique guide brings together the physiological, structural, molecular biological, and theoretical aspects of the signal transduction network that regulates growth and proliferation in normal and tumor cells. It provides comprehensive survey of functional and theoretical features of intracellular signal processing and introduces the concept of cellular self-organization. Exemplified by oscillatory calcium waves, strategies for the design of computer experiments are presented that can assist or even substitute for time-consuming biological experiments. The presented minimal model for proliferation-associated signal transduction clearly shows the alterations of the cellular signal network involved in neoplastic growth. This book will be useful to cell and molecular biologists, oncologists, physiologists, theoretical biologists, computer scientists, and all other researchers and students studying functional aspects of cellular signaling.

About the Author

Michael Kraus, Bernhard Wolf