Study the Effect of Formulation and Inprocess Parameters on Pellets: Extrusion and Spheronization Techniques

Sharma, Anshuli, Chaurasia, Sandhya, Vasireddy, Suneel kumar

ISBN 10: 3659199648 / ISBN 13: 9783659199646

Published by LAP LAMBERT Academic Publishing, 2012

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Bibliographic Details

• Title: Study the Effect of Formulation and Inprocess Parameters on Pellets: Extrusion and Spheronization Techniques
• Publisher: LAP LAMBERT Academic Publishing
• Publication Date: 2012
• Language: English
• ISBN 10: 3659199648
• ISBN 13: 9783659199646
• Binding: Paperback
• Condition: Like New
• Book Type: book

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Synopsis

This study was to investigate the effect of formulation variables like Microcrystalline cellulose (MCC), Lactose, Dicalcium phosphate dihydrate (DCPD), Starch 1500, Pearlitol 200sd etc. which are widely used tabeleting excipients. These diluents were used individually and in combination with MCC. Binders like Hydroxypropyl cellulose (HPC-sL), Polyvinylpyrrrolidone-K 30, were used to study their effect on pellet properties. The pellets prepared were analyzed for the properties like their shape (aspect ratio), size distribution, smoothness, bulk density, tapped density, car index, hausner ratio, Loss on drying and yield.

About the Author

Anshuli Sharma completed her M pharmacyfrom Mahamaya Technical UniversityNoida (U.P.) Anshuli Sharma having excellent academics record.