A Study of Fast Dissolving Tablets of Febuxostat: Formulation and Evaluation

Solanki, Kinjal, Pillai, Archana, Dholakia, Sandip

ISBN 10: 6202563761 / ISBN 13: 9786202563765

Published by LAP LAMBERT Academic Publishing, 2020

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Seller Inventory # ERICA82362025637616

Bibliographic Details

• Title: A Study of Fast Dissolving Tablets of Febuxostat: Formulation and Evaluation
• Publisher: LAP LAMBERT Academic Publishing
• Publication Date: 2020
• Language: English
• ISBN 10: 6202563761
• ISBN 13: 9786202563765
• Binding: paperback
• Condition: New
• Book Type: book

About this title

Synopsis

The idea of formulating Fast Dissolving Tablets of Febuxostat is to provide an acceptable and practical approach for the objectives of faster disintegrating and dissolution characteristics. In the current work Fast Dissolving Tablets of Febuxostat were prepared by sublimation technique after preparing solid dispersion of Febuxostat in which co- precipitation gives high solubility in ratio of 1:0.5:1.2 (Drug: PEG 6000: Mannitol) , using sodium starch glycolate, croscarmellose sodium, kyron T -134 and kyron T-314. All the Fast Dissolving Tablets of Febuxostat were subjected to thickness, diameter, hardness, friability, weight variation, disintegration time, wetting time, water absorption ratio and drug content uniformity.