Substance P: From Pain to Cancer, a volume in the
Molecular Mediators in Health and Disease: How Cells Communicate series
, provides a complete discussion of substance P biology, its role in normal physiology and a variety of diseases.
The volume provides an introduction to substance P and its pharmacology, followed by exploring its role across the human body including cardiovascular function, micturition, learning and memory, emesis, respiration and sleep. It then discusses the critical role of substance P in several disease states including acute brain injury, neurodegeneration, seizures, depression and anxiety, cancer, musculoskeletal disorders, and viral infection, including COVID-19. The book closes with a look towards future perspectives for substance P.
Substance P: From Pain to Cancer is an ideal reference for researchers across the life sciences interested in understanding the role of this multi-functioning mediator and its biological significance.
- Provides a comprehensive overview of the role of substance P across different organ systems, including the nervous, cardiovascular and musculoskeletal systems and renal function
- Includes detailed coverage of the specific actions of substance P in various disease states and conditions, such as inflammation, cancer, acute brain injury, mood disorders, Parkinson’s disease, Alzheimer’s disease and viral infection including COVID-19
- Examines substance P as a modulator of the immune response and pain perception
- Includes expertise from a range of interdisciplinary areas including molecular biology, pharmacology, physiology, neuroscience, anatomy, and therapeutics
Robert Vink is an Emeritus Professor at the University of South Australia and is currently Chair of the Board for Connectivity: Traumatic Brain Injury Australia. He was previously appointed as the Professor and Chair of Neurosurgical Research and Head of School, Medical Sciences at the University of Adelaide, Australia. Throughout his time as a teaching/research academic he led a highly productive research group and maintained an extensive publication output. He is the author of over 260 articles and book chapters. He has supervised more than 30 graduate research students, many of whom now hold significant academic and other positions throughout Australia and internationally.
He is known internationally for his work in traumatic brain injury and has received numerous prestigious awards and appointments related to this. He currently provides research consulting services to universities and the pharmaceutical industry.
