Susceptibility to Infectious Diseases : The Importance of Host Genetics

23x15cm, xvi,398,(8)pp, Series: Advances in Molecular and Cellular Microbiology, 4. Contains 13 papers. Includes: Application of genetic epidemiology to dissecting host susceptibility/resistance to infection illustrated with the study of common mycobacterial infections; The diverse genetic basis of immunodeficiencies; Genetic diversity in the major histocompatibility complex and the immune response to infectious diseases; The cystic fibrosis transmembrane conductance regulator; The influence of inherited traits on malaria infection; Polymorphic chemokine receptor and ligand genes in HIV infection; N-ramp and resistance in intracellular pathogens; The interleukin-12-interferon-g loop is required for protective immunity to experimental and natural infections by Mycobacterium; Mannose-binding lectin deficiency and susceptibility to infectious disease; Blood group phenotypes and infectious diseases; Genetics of human susceptibility to infection and hepatic disease caused by schistosomes; Genetic susceptibility to prion diseases. …