The Synaptic Organization of the Brain

. Ed(s): Shepherd, Gordon M., MD. DPhil.

ISBN 10: 019515956X / ISBN 13: 9780195159561

Published by Oxford University Press, U.S.A., 2003

About this Item

This is a thorough revision of the standard text on local circuits in the different regions of the brain. In this fifth edition, the results of the mouse and human genome projects are incorporated for the first time. Also for the first time, the reader is oriented to supporting neuroscience databases. Editor(s): Shepherd, Gordon M., MD. DPhil. Num Pages: 736 pages, numerous line drawings & halftones. BIC Classification: MFG; MJN; PSAN; PSD. Category: (P) Professional & Vocational. Dimension: 235 x 168 x 33. Weight in Grams: 1184. . 2003. 5th Edition. paperback. . . . .

Seller Inventory # V9780195159561

Bibliographic Details

• Title: The Synaptic Organization of the Brain
• Publisher: Oxford University Press, U.S.A.
• Publication Date: 2003
• Language: English
• ISBN 10: 019515956X
• ISBN 13: 9780195159561
• Binding: Soft cover
• Edition: 5th or later Edition
• Condition: New

About this title

Synopsis

It is widely recognized that the neural basis of brain function can be fully understood only by integrating many disciplines at many levels. Studies of synaptic organization are bringing about a quiet revolution in achieving this goal, as documented by this unique book over the past 30 years. In this fifth edition, the results of the mouse and human genome projects are incorporated for the first time. Molecular biologists interested in functional genomics and proteomics of the brain will find answers here to the critical questions: what are the cell and circuit functions of gene products? Also for the first time, the reader is oriented to supporting neuroscience databases. Among the new advances covered are 2-photon confocal laser microscopy of dendrites and dendritic spines, biochemical analyses, and dual patch and multielectrode recordings, applied together with an increasing range of behavioral and gene-targeting methods. Leading experts in the best understood brain regions bring together the molecular, anatomical, functional, and behavioral data in authoritative integrated accounts. The chapters are organized in the same format, covering the neural elements, synaptic connections, basic circuits, physiology, neurotransmitters, neuromodulators, membrane properties, dendritic properties, and with a final section on how the circuits mediate specific behaviors. The uniform framework for each chapter enables the authors to higlight the principles that are common to all regions, as well as the adaptations unique to each, thus serving as a model for understanding the neural basis of behavior.

About the Author

Gordon M. Shepherd is at Yale University School of Medicine.