Synthesis Of Compounds Containing 9(10H)-Acridone: Synthesis Of Some New Heterocyclic Compounds Containing 9(10H)-Acridone, And Studying Their Biological Activity

Hameed, Ayad; Yousif, Emad; Kreem, Ayad; Hameed, Ayad; Yousif, Emad; Kreem, Ayad

ISBN 10: 384432786X / ISBN 13: 9783844327861

Published by Lap Lambert Academic Publishing, 2011

About this Item

88 pages. 8.66x5.91x0.20 inches. In Stock.

Seller Inventory # __384432786X

Bibliographic Details

• Title: Synthesis Of Compounds Containing 9(10H)-Acridone: Synthesis Of Some New Heterocyclic Compounds Containing 9(10H)-Acridone, And Studying Their Biological Activity
• Publisher: Lap Lambert Academic Publishing
• Publication Date: 2011
• Language: English
• ISBN 10: 384432786X
• ISBN 13: 9783844327861
• Binding: Paperback
• Condition: Brand New
• Weight: 0.18 kilograms

About this title

Synopsis

Acridone derivatives containing 1, 3, 4-oxadiazole and 1, 3, 4-thiadiazole rings are synthesized.Diphenylamine-2,4'-dicarboxylic acid [1] is obtained in a high yield by refluxing a mixture of 4-aminobenzoic acid and 2-chloro benzoic acid in the presence of catalytic amount of copper oxide. 9(10H)-Acridone-2-carboxylic acid [2] is synthesized in ring closure reaction by heating compound [1] in sulfuric acid followed by basic hydrolysis.Reaction of compound [2] with thiosemicarbazide in the presence of phosphorus oxychloride gave 2-[5-amino-1, 3, 4-thiadiazole-2-yl]-9(10H)-acridone

About the Author

Ayad Hameed, Emad Yousif and Ayad Kreem, Department of Chemistry, College of Science, AL-Nahrain University, Baghdad, Iraq. Jumat Salimon and Nadia Salih,School of Chemical Science and Food Technology, Faculty of Science and Technology, Universiti Kebangsaan Malaysia, 43600 Bangi, Selangor, Malaysia