Synthesis & Evaluation of 2&6-Substituted 4H-Chromen-4-One Derivatives | As An Anti-inflammatory & Anti-oxidants Agents

Chirag J. Patel (u. a.)

ISBN 10: 3659345490 / ISBN 13: 9783659345494

Published by LAP LAMBERT Academic Publishing, 2013

About this Item

Synthesis & Evaluation of 2&6-Substituted 4H-Chromen-4-One Derivatives | As An Anti-inflammatory & Anti-oxidants Agents | Chirag J. Patel (u. a.) | Taschenbuch | 100 S. | Englisch | 2013 | LAP LAMBERT Academic Publishing | EAN 9783659345494 | Verantwortliche Person für die EU: BoD - Books on Demand, In de Tarpen 42, 22848 Norderstedt, info[at]bod[dot]de | Anbieter: preigu.

Seller Inventory # 106065134

Bibliographic Details

• Title: Synthesis & Evaluation of 2&6-Substituted 4H-Chromen-4-One Derivatives | As An Anti-inflammatory & Anti-oxidants Agents
• Publisher: LAP LAMBERT Academic Publishing
• Publication Date: 2013
• Language: English
• ISBN 10: 3659345490
• ISBN 13: 9783659345494
• Binding: Taschenbuch
• Condition: Neu
• Dimensions: 220W x 150H x 6D millimeters 220 millimeters width by 150 millimeters height by 6 millimeters depth
• Weight: 167 grams
• Seller catalogs:
  • Bücher

About this title

Synopsis

The present investigation is concerned with synthesis of new 2 and 6 - substituted 4H-chromen-4-One derivatives with the objectives of discovering novel and potent anti-inflammatory agents and anti-oxidants. The results of anti-inflammatory activity were revealed that the compound has indole 2 substitution with 4-nitrophenyl amino methyl (at 6th position) on 4H- chromen–4–one having more anti-inflammatory activity as compared to other substituent’s. While, indole 2 substituted 4-methoxy phenyl amino methyl (at 6th position) 4H–chromen–4–one showed outperformed anti-oxidant activity in different anti-oxidant model as compared to other substituent’s. The all newly synthesized compounds displayed moderate to potent anti-inflammatory and anti-oxidant activity and has therapeutic potential in combating this devastating inflammatory and oxidative condition of the body, might be deserve promising substances for further in vivo evaluation as anti-inflammatory and anti-oxidant properties. However the anti-inflammatory activity is not related to antioxidant potential.

About the Author

Prof. Chirag J. Patel, Ph.D. fellow in Pharmaceutical Sciences at K.S.K.V. Kachchh University, Bhuj-Kachchh, Gujarat, INDIA. Field of Study: Phytopharmacoligal Screening of Some Laticiferous Plants & Drug Design with Development. Presently working as an Associate Professor at Veerayatan Institute of Pharmacy, India from last seven years.