Synthesis & Study Biological Activity of New Phthalimide Derivatives : Study the biological activity of new Mannich bases derived from phthalimide

Language: English

Published by LAP LAMBERT Academic Publishing, 2019

6200499683 / 9786200499684

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nach der Bestellung gedruckt Neuware - Printed after ordering - The research involves synthesis of some new aminoacetylenic derivatives of phthalimide. The phthalimide in this study served as starting material and was converted to the corresponding potassium salt through reaction with potassium hydroxide. The alkylation of the imide salt with the propargyl bromide afforded the desired N-propynylphthalimide (A1). The Mannich reaction (three componenets in one pot reaction) was carried out by using the N-propynylphthalimide (A1), formaldehyde, benzaldehyde and some of its derivatives, as well as morpholine or piperidine which are taken as secondary amines, in the presence of peroxide free dioxane and a catalytic amount of cuprous chloride under various basic, acidic, solvent and temperature conditions, resulted in formation of a novel aminoacetylenic Isoindoline-1,3-dione derivatives (A2-A12).

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Title
Synthesis & Study Biological Activity of New Phthalimide Derivatives : Study the biological activity of new Mannich bases derived from phthalimide
Author
Asaad Hashim
Publisher
LAP LAMBERT Academic Publishing
Publication year
2019
Condition
Neu
Binding
Taschenbuch
Language
English
ISBN 10
6200499683
ISBN 13
9786200499684
Item weight
155 grams
Dimensions
220x150x7 mm

AHA-BUCH GmbH

Einbeck, Germany

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AbeBooks seller since August 14, 2006

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