Title: Systems Analysis of Human Multigene Disorders: 799 (Advances in Experimental Medicine and Biology)
Publisher: Springer
Publication Date: 2017
Language: English
ISBN 10: 1493951947
ISBN 13: 9781493951949
Binding: Soft cover
Condition: New

About this title

Synopsis

Understanding the genetic architecture underlying complex multigene disorders is one of the major goals of human genetics in the upcoming decades. Advances in whole genome sequencing and the success of high throughput functional genomics allow supplementing conventional reductionist biology with systems-level approaches to human heredity and health as systems of interacting genetic, epigenetic, and environmental factors. This integrative approach holds the promise of unveiling yet unexplored levels of molecular organization and biological complexity. It may also hold the key to deciphering the multigene patterns of disease inheritance.

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