Systems Biology: Simulation of Dynamic Network States
Language: English
Published by Cambridge University Press, 2011
- Hardcover
- Used
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Used - Acceptable: All pages and the cover are intact, but shrink wrap, dust covers, or boxed set case may be missing. Pages may include limited notes, highlighting, or minor water damage but the text is readable. Item may be missing bundled media.
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- Title
- Systems Biology: Simulation of Dynamic Network States
- Author
- Palsson, Bernhard Ø.
- Publisher
- Cambridge University Press
- Publication year
- 2011
- Condition
- acceptable
- Binding
- Hardcover
- Language
- English
- ISBN 10
- 1107001595
- ISBN 13
- 9781107001596
Biophysical models have been used in biology for decades, but they have been limited in scope and size. In this book, Bernhard Ø. Palsson shows how network reconstructions that are based on genomic and bibliomic data, and take the form of established stoichiometric matrices, can be converted into dynamic models using metabolomic and fluxomic data. The Mass Action Stoichiometric Simulation (MASS) procedure can be used for any cellular process for which data is available and allows a scalable step-by-step approach to the practical construction of network models. Specifically, it can treat integrated processes that need explicit accounting of small molecules and protein, which allows simulation at the molecular level. The material has been class-tested by the author at both the undergraduate and graduate level. All computations in the text are available online in MATLAB and MATHEMATICA® workbooks, allowing hands-on practice with the material.
"Synopsis" may belong to another edition of this title.
About the Author
Bernhard Ø. Palsson is the Galletti Professor of Bioengineering and Adjunct Professor of Medicine at the University of California, San Diego.
"About the title" may belong to another edition of this title.
clickgoodwillbooks
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