T-cell Receptor Gamma Gene Rearrangement in T-cell Neoplasm: Detection Using Genescan

Eman Adel

ISBN 10: 3659859095 / ISBN 13: 9783659859090

Published by LAP LAMBERT Academic Publishing, 2016

About this Item

176 pages. 8.66x5.91x0.40 inches. In Stock.

Seller Inventory # 3659859095

Bibliographic Details

• Title: T-cell Receptor Gamma Gene Rearrangement in T-cell Neoplasm: Detection Using Genescan
• Publisher: LAP LAMBERT Academic Publishing
• Publication Date: 2016
• Language: English
• ISBN 10: 3659859095
• ISBN 13: 9783659859090
• Binding: Paperback
• Condition: Brand New
• Weight: 0.31 kilograms

About this title

Synopsis

The discrimination between reactive and malignant cell populations in some patients with suspected T-cell lymphoproliferative disorders can be complicated and less straightforward. Often, the dilemma lies in determining whether a population of lymphocytes is reactive or neoplastic. In such cases, T-cell receptor (TCR)gene clonality studies have proved useful as an additional diagnostic tool. The TCRγ gene is a preferred target for TCR gene clonality as it is rearranged at an early stage of T lymphoid development, rearranged in a large percent of T-cell neoplasms, and also because of its relative structural simplicity.

About the Author

Eman A. Soliman, M.Sc, studied at faculty of Science at Mansoura University. Works as a medical analysis specialist in Oncology center at Mansoura University. Expert in molecular biology fields including PCR, Genescan and Sequencing techniques.