T-type Calcium Channels in Basic and Clinical Science

Stephen W. Schaffer (u. a.)

ISBN 10: 3709114128 ISBN 13: 9783709114124

Published by Springer, 2014

Language: English

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Bibliographic Details

Title

T-type Calcium Channels in Basic and Clinical Science

Publisher

Springer

Publication Date

2014

Language

English

ISBN 10

3709114128

ISBN 13

9783709114124

Binding

Buch

Condition

Neu

Dimensions

Weight

418 grams

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B�cher

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Synopsis

T-type calcium channels are prevalent in every organ of the body, and are believed to play a part in a variety of physiological processes, including contraction, shape change, secretion, endo- and exocytosis, cell proliferation and differentiation, modulation of enzyme function, and cell cycle progression. As such, research on the roles of these channels in a wide range of diseases has attracted increasing attention in recent years. The purpose of this book is to present a series of unique and comprehensive reviews of our current understanding of T-type calcium channels at the level of the basic sciences as well as the clinical sciences. For key organ systems, information is provided on the correlation between the molecular, biophysical and pharmacological properties of the channels, their cellular mechanisms, and their potential roles in the pathogenesis of various diseases. The compilation presents both commonplace and less well-known findings on these channels in a format designed to appeal to both casual readers and specialists in basic and clinical research on these transporters.

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