TRACE ELEMENTS, MICRONUTRIENTS, AND FREE RADICALS (HB)

DREOSTI I.E.

ISBN 10: 0896031888 / ISBN 13: 9780896031883

Published by SP SPRINGER, 1992

About this Item

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Seller Inventory # CVS 9780896031883

Bibliographic Details

• Title: TRACE ELEMENTS, MICRONUTRIENTS, AND FREE RADICALS (HB)
• Publisher: SP SPRINGER
• Publication Date: 1992
• Language: English
• ISBN 10: 0896031888
• ISBN 13: 9780896031883
• Binding: Hardcover
• Edition: International Edition
• Condition: New

About this title

Synopsis

Itisonlyrecently thatthe naturaloccurrenceoffree radicalsin biological tissue has become widely accepted, and that the suspi- cion with which biologists previously viewed the free radicals of radiationchemistryhas beenplacedin a broaderperspective. Now, oxygen-derived free radicals are considered respectable biochemi- cal intermediates, given always the caveat that unwanted tissue damage may arise if these active species are produced in such abundance that they overwhelm the natural antioxidant and free- radical defense mechanisms, or if these systems have become hypoeffective. Many factors, including several dietary manipula- tions, can lead toelevatedproductionofsuperoxide and may result in free radical overload, whereas a deficiency of those micronutri- ents associated with the antioxidant defense mec.hanisms may re- sult in substantially diminished antioxidant capacity. By now, antioxidants have become a household word and al- most everyone is aware of their imponance in protecting the body against attack by active oxygen species. Indeed, it is a paradox of nature that oxygen, which is so essential to sustain aerobic life, ul- timately contributes to its destruction. Not surprisingly, recogni- tion ofthis dilemma has generated a spate ofantioxidant strategies intended to reduce the risk of tissue damage by rampant oxygen radicals, some sadly based less on science than on speculation.

Review

...Highly recommend[ed].-Journal of Medicinal Chemistry