READ THE WINNER OF 9 NATIONAL AND INTERNATIONAL BOOK AWARDS!
- "A marvelous book that's packed with knowledge, insight, and hope...he writes with admirable clarity."- Kirkus Reviews
- "This book bursts with good news." Booklife Reviews by Publisher's Weekly
Step inside the revolution in cancer medicine with Dr. Drew N. Kelner, Ph.D., a biochemist, cancer drug developer, and former scientific leader at the biopharmaceutical company Amgen, and learn how a century of groundbreaking discoveries in the biomedical sciences have ripped the lid off of cancer's black box of molecular secrets, revealing how tumors corrupt our biology to evade immunity and resist every therapeutic intervention we devise.
Through vivid storytelling and with a knack for explaining complex scientific concepts in accessible language, readers meet the innovators behind "living drugs"-medicines made in biological systems, including engineered T cells (CAR-T cells), oncolytic viruses, and other seemingly magical medicines-that are changing the paradigm of cancer treatment from the traditional therapeutic triad of "cut, burn, and poison" that destroys both tumors and normal cells to targeted therapies that arrest tumor progression and metastasis and empower the immune system to seek out and destroy tumors.
For some patients, these emerging "wonder drugs" are providing long-term remissions measured in years; for the most fortunate patients, even decades of remission have already been achieved.
Taming Cancer presents a compelling and hopeful vision of a future when cancer will be managed as a chronic disease, much like rheumatoid arthritis and diabetes. For the most responsive patients, the eradication of cancer cells from the body-the long-sought cure for metastatic cancer-will become a reality for increasing numbers of patients.
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For the past 35 years, I've been a biochemist and immunologist engaged in the development of biopharmaceutical drugs-proteins (such as antibodies), engineered immune cells, and even engineered viruses (it's in Chapter 14)-that target human diseases at the molecular level. During my career, I've had the great privilege of participating in the development of innovative medicines for cancer, hemophilia, anemia, osteoporosis, and rheumatoid arthritis that have been used by millions of people around the world. I was born and raised on Long Island and left home to pursue a B.S. in chemistry from Haverford College and a Ph.D. in biochemistry from Duke University. I am currently the President of Shenandoah Biotechnology Consulting, LLC, in Charlottesville, VA, where I reside with my beloved wife Deb. This book is the product of a long and exhilarating career in the scientific trenches of the biopharmaceutical industry and a seemingly natural consequence of my lifelong preoccupation: biology and medicine. I wrote Taming Cancer to pay forward the privilege I had of working at the leading edge of cancer drug development and to send a message of hope to cancer patients and their families throughout the world.
Questions and/or comments are welcome at tamingcancerbook@gmail.com If you don't mind leaving an honest review, I would be grateful for the feedback!.