Targeted Metabolomics: Improved Detection and Quantification of Drugs

Daxesh Patel

ISBN 10: 6203041203 / ISBN 13: 9786203041200

Published by LAP LAMBERT Academic Publishing Nov 2020, 2020

About this Item

Neuware -Pharmacokinetic and bio-equivalency studies require very precise and accurate assay methods that are well-validated to quantify drugs in biological samples. The assay methods have to be sensitive enough to determine the biological sample concentration of the drug and/or its metabolite(s) for a period of about five elimination half-lives after the dosage of the drug. The assay methods also have to be very selective to ensure reliable data, free from the interference of endogenous98 compounds in the biological samples. In addition, methods have to be as robust and cost-effective as possible, making of particular importance to bioequivalent studies. Above all, the assay methods must be able to withstand the inspection of national drug registration authorities who judge them on the basis of criteria established by worldwide harmony.Books on Demand GmbH, Überseering 33, 22297 Hamburg 276 pp. Englisch.

Seller Inventory # 9786203041200

Bibliographic Details

• Title: Targeted Metabolomics: Improved Detection and Quantification of Drugs
• Publisher: LAP LAMBERT Academic Publishing Nov 2020
• Publication Date: 2020
• Language: English
• ISBN 10: 6203041203
• ISBN 13: 9786203041200
• Binding: Taschenbuch
• Condition: Neu
• Dimensions: 220W x 150H x 17D millimeters 220 millimeters width by 150 millimeters height by 17 millimeters depth
• Weight: 429 grams

About this title

Synopsis

Pharmacokinetic and bio-equivalency studies require very precise and accurate assay methods that are well-validated to quantify drugs in biological samples. The assay methods have to be sensitive enough to determine the biological sample concentration of the drug and/or its metabolite(s) for a period of about five elimination half-lives after the dosage of the drug. The assay methods also have to be very selective to ensure reliable data, free from the interference of endogenous98 compounds in the biological samples. In addition, methods have to be as robust and cost-effective as possible, making of particular importance to bioequivalent studies. Above all, the assay methods must be able to withstand the inspection of national drug registration authorities who judge them on the basis of criteria established by worldwide harmony.