A Textbook of Drug Design and Development

This second edition has lost none of the brilliance for which the first edition was noted. It has been improved by bringing it up-to-date and adapting the text to make it clearer and more understandable for undergraduate and graduate students. It is the natural choice of textbooks in this rapidly advancing field.
A Textbook of Drug Design and Development is a book of beautiful simplicity and structure. It starts with an informative overview of the topics of drug discovery and follows the individual stages of drug design and development from the initial elucidation of a structure-activity relationship to the final processes of clinical evaluation and registration. Topics examined include the design of drugs for particular cellular targets such as ion channels and receptors; specific classes of drug, such as peptidomimetics, anvirals, and anticancer agents; the use of gene technology in pharmaceutical research; and the design and application of prodrugs to improve drug delivery.