Three-Dimensional Electron Microscopy of Macromolecular Assemblies: Visualization of Biological Molecules in Their Native State

Frank, Joachim

ISBN 10: 0195150961 / ISBN 13: 9780195150964

Published by Oxford University Press, 2006

About this Item

New book, never read. Still in shrinkwrap. Pages clean and crisp, spine unbroken. 1019B.

Seller Inventory # A1019-116

Bibliographic Details

• Title: Three-Dimensional Electron Microscopy of Macromolecular Assemblies: Visualization of Biological Molecules in Their Native State
• Publisher: Oxford University Press
• Publication Date: 2006
• Language: English
• ISBN 10: 0195150961
• ISBN 13: 9780195150964
• Binding: Hardcover
• Edition: 2nd Edition
• Condition: New

About this title

Synopsis

Cryoelectron microscopy of biological molecules is among the hottest growth areas in biophysics and structural biology at present, and Frank is arguably the most distinguished practitioner of this art. CryoEM is likely over the next few years to take over much of the structural approaches currently requiring X-ray crystallography, because one can now get good and finely detailed images of single molecules down to as little as 200,000 MW, covering a substantial share of the molecules of greatest biomedical research interest. This book, the successor to an earlier work published in 1996 with Academic Press, is a natural companion work to our forthcoming book on electron crystallography by Robert Glaeser, with contributions by six others, including Frank. A growing number of workers will employ CryoEM for structural studies in their own research, and a large proportion of biomedical researchers will have a growing interest in understanding what the capabilities and limits of this approach are.

About the Author

Joachim Frank is at Howard Hughes Medical Institute.