Toxicologic Emergencies clinical reference 2027: Poisoning Recognition, Antidote Therapy, and Evidence-Based Management of Overdose, Envenomation, and Toxic Exposures

THE POISONED PATIENT RARELY ANNOUNCES THE DIAGNOSIS.

A urine screen says nothing about most of the drugs that kill. A patient who looks well after a sustained-release ingestion can deteriorate overnight. An antidote given to the wrong patient can cause the harm it was meant to prevent. Toxicologic Emergencies Clinical Reference 2027 is built around the reasoning that turns an uncertain presentation into the right treatment at the right time.

Seventeen chapters move from the structured approach to the poisoned patient through decontamination, the laboratory and the electrocardiogram, and then across the agents that fill emergency departments: analgesics and nonprescription products, cardiovascular drugs, antidepressants and antipsychotics, lithium and the anticonvulsants, sedative-hypnotics and withdrawal, opioids and the changing drug supply, stimulants and novel substances, methanol and the glycols, cellular asphyxiants, pesticides and caustics, envenomations, plants and mushrooms, and the populations in whom poisoning behaves differently.

WRITTEN THE WAY THE WORK ACTUALLY HAPPENS

Every chapter opens with a real patient and a question. The numbered sections supply the mechanism, the recognition, the investigations and the evidence. The chapter closes by returning to that patient and following the decisions to an outcome.

• TOX PEARL panels carry the practical points experienced clinicians rely on
• DANGER SIGNAL panels mark the findings that demand action before results return
• ANTIDOTE AND DOSING panels give regimens with the verification note that must follow them
• TOXIDROME COMPASS panels separate the syndromes that look alike at the bedside
• TABLES gather antidote regimens, treatment thresholds and extracorporeal treatment criteria for rapid consultation

CURRENT, REFERENCED, AND BUILT FOR PRINT

The content reflects what has changed: illicitly manufactured fentanyl, nitazenes and veterinary sedative adulterants, emergency department buprenorphine after the waiver was removed, the 2023 United States and Canadian acetaminophen consensus, updated extracorporeal treatment recommendations, and revised resuscitation guidance for poisoning. Recommendations name their issuing body and year, and the back matter carries a full reference list in a style based on the American Medical Association Manual of Style.

OVER ONE HUNDRED FULL-COLOR CLINICAL PHOTOGRAPHS, three appendices covering antidotes, laboratory and toxic concentration values, and toxidrome and dialysis quick reference, plus a glossary, abbreviations list and full index, in a LARGE 8.5 BY 11 INCH FORMAT.

This book is an educational reference for qualified clinicians. It does not replace clinical training, judgment, supervision, the current local formulary, or advice from a regional poison center.