Toxicology : Principles and Methods

Contents 1 Introduction 2 Toxic Substances 3 Toxicity 4 Routes of Exposure of Toxicants 5 Absorption of Toxicants 6 Distribution of Toxicants 7 Excretion of Toxicants 8 Biotransformation 9 Mode of Action of Xenobiotics  10 Target-Site Interactions 11 Combined Action of Toxicants 12 Dose?Response Relationship 13 Teratogens 14 Carcinogens 15 Mutagens 16 Safety Evaluation of Toxicants 17 Cell Injury 18 Toxicity at the Level of Rgans and Organ Systems 19 Impact of Pollutants on Quatic Organisms 20 Environmental Toxicology 21 Persistence and Residual Nature of Toxicants 22 Basics of Nutritional Toxicology 23 Liver Function Tests In Toxicology 24 Antidotal Procedures Treatment of Intoxication 25 Selected Toxicological Methods Appendices Glossary References IndexThe study of toxicants-their route of entry their absorption distribution elimination and transformation and their dynamics within organisms and the environment-have been clearly dealt with in this book It provides a concise well-balanced and technical introduction to toxicology with focus on the basic principles and concepts It would prove to be a complete study unit for new entrants to this field The chapter Impact of pollutants on aquatic organisms has been written exclusively based on the authors laboratory observations 350 pp.…