Transcriptional interference

Alexei Protsenko

ISBN 10: 6203571660 / ISBN 13: 9786203571660

Published by Our Knowledge Publishing Jun 2021, 2021

About this Item

This item is printed on demand - it takes 3-4 days longer - Neuware -Transcriptional interference results from the existence of two promoters and involves a direct negative effect of one transcriptional activity on the second transcriptional activity, exists as an integral part of the genome and represents the basis for the regulation of gene activity. It was first discovered in genes defining the lytic or lysogenic pathway of temperate coliphage 186, where the strong lytic promoter reduces the activity of the weak, convergent-layered, lysogenic promoter several-fold. Repression of the lytic promoter prevents interference and thus provides the positive autoregulation required to maintain a stable lysogenic state. Transcriptional interference is widespread and has been shown for many organisms and genetic systems, but never for restriction-modification systems.Transcriptional interference results from the existence of two promoters and involves a direct negative effect of one transcriptional activity on the second transcriptional activity, exists as an integral part of the genome and represents the basis for the regulation of gene activity. It was first discovered in genes defining the lytic or lysogenic pathway of temperate coliphage 186, where the strong lytic promoter reduces the activity of the weak, convergent-layered, lysogenic promoter several-fold. Repression of the lytic promoter prevents interference and thus provides the positive autoregulation required to maintain a stable lysogenic state. Transcriptional interference is widespread and has been shown for many organisms and genetic systems, but never for restriction-modification systems. 88 pp. Englisch.

Seller Inventory # 9786203571660

Bibliographic Details

• Title: Transcriptional interference
• Publisher: Our Knowledge Publishing Jun 2021
• Publication Date: 2021
• Language: English
• ISBN 10: 6203571660
• ISBN 13: 9786203571660
• Binding: Taschenbuch
• Condition: Neu
• Dimensions: 220W x 150H x 6D millimeters 220 millimeters width by 150 millimeters height by 6 millimeters depth
• Weight: 149 grams

About this title

Synopsis

Transcriptional interference results from the existence of two promoters and involves a direct negative effect of one transcriptional activity on the second transcriptional activity, exists as an integral part of the genome and represents the basis for the regulation of gene activity. It was first discovered in genes defining the lytic or lysogenic pathway of temperate coliphage 186, where the strong lytic promoter reduces the activity of the weak, convergent-layered, lysogenic promoter several-fold. Repression of the lytic promoter prevents interference and thus provides the positive autoregulation required to maintain a stable lysogenic state. Transcriptional interference is widespread and has been shown for many organisms and genetic systems, but never for restriction-modification systems.<p>Transcriptional interference results from the existence of two promoters and involves a direct negative effect of one transcriptional activity on the second transcriptional activity, exists as an integral part of the genome and represents the basis for the regulation of gene activity. It was first discovered in genes defining the lytic or lysogenic pathway of temperate coliphage 186, where the strong lytic promoter reduces the activity of the weak, convergent-layered, lysogenic promoter several-fold. Repression of the lytic promoter prevents interference and thus provides the positive autoregulation required to maintain a stable lysogenic state. Transcriptional interference is widespread and has been shown for many organisms and genetic systems, but never for restriction-modification systems.</p>