Transcriptome Profiling: Progress and Prospects

Transcriptome Profiling: Progress and Prospects assists readers in assessing and interpreting a large number of genes, up to and including an entire genome. It provides key insights into the latest tools and techniques used in transcriptomics and its relevant topics which can reveal a global snapshot of the complete RNA component of a cell at a given time. This snapshot, in turn, enables the distinction between different cell types, different disease states, and different time points during development.

Transcriptome analysis has been a key area of biological inquiry for decades. The next-generation sequencing technologies have revolutionized transcriptomics by providing opportunities for multidimensional examinations of cellular transcriptomes in which high-throughput expression data are obtained at a single-base resolution. Transcriptome analysis has evolved from the detection of single RNA molecules to large-scale gene expression profiling and genome annotation initiatives.

Written by a team of global experts, key topics in Transcriptome Profiling include transcriptome characterization, expression analysis of transcripts, transcriptome and gene regulation, transcriptome profiling and human health, medicinal plants transcriptomics, transcriptomics and genetic engineering, transcriptomics in agriculture, and phylotranscriptomics.

• Presents recent development in the tools and techniques in transcriptomic characterization
• Integrates expression analysis of transcripts and gene regulation
• Includes the application of transcriptomics in human health, genetic engineering and agriculture

Mohammad Ajmal Ali is an Associate Professor in the Department of Botany and Microbiology at King Saud University in Riyadh, Saudi Arabia, where he has taught molecular biology and bionanotechnology since 2010. He received his M.S. (1999) and Ph.D. (2006) degrees in Botany from TM Bhagalpur University in Bihar, India, and pursued postdoctoral research at Korea Research Institute of Biosciences and Biotechnology in Daejeon, South Korea. Ali's research program encompasses next-generation sequencing, computational chemistry, bioprospecting and bionanotechnology. He has authored/co-authored eight books and over 200 research articles in more than 52 journals of international repute.

Joongku Lee is a Professor in the Department of Environment and Forest Resources at Chungnam National University in Daejeon, South Korea. He received Ph.D. (1998) from the Department of Biology at SungKyunKwan University, South Korea. He conducted postdoctoral work at Jepson Herbarium and Department of Integrative Biology at the University of California, Berkeley, USA. Lee’s present research program encompasses next-generation sequencing, bioprospecting, and plant phylogeny. He has authored/co-authored 17 books and 171 publications.