Title: Tuberous Sclerosis Complex : From Basic Science to Clinical Phenotypes
Publisher: Mac Keith Press
Publication Date: 2003
Language: English
ISBN 10: 1898683395
ISBN 13: 9781898683391
Binding: Hardcover
Condition: New

About this title

Synopsis

"This is clearly the most authoritative and contemporary statement of current knowledge yet published."
from the Foreword by H. Sarnat

Tuberous sclerosis is the prototype of a category of malformations uniquely characterized by disturbances in cellular differentiation and growth. It presents with a complex association of different neurological phenotypes, including seizures, cognitive impairments and autism. It is important not only because it is a relatively common hereditary neurological disease with high morbidity, but because it has implications in other pathological processes, such as dysplasia and neoplasia, hamartoma formation and other disturbances in morphogenic processes.

This book correlates new genetic data and basic science, covers clinical presentation, reviews the historical background and current diagnostic criteria, and deals with the recent advances in neuropathology, molecular genetics and neurobiology which give a better understanding of the pathogenesis of the disease.

Paediatricians and child neurologists will find this book uniquely useful.

About the Author

Edited by Paolo Curatolo, Universit� degli Studi di Roma 'Tor Vergata'

"About this title" may belong to another edition of this title.

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