The Tumor Immunoenvironment

Michael R Shurin

ISBN 10: 940076216X / ISBN 13: 9789400762169

Published by Springer, Springer Apr 2013, 2013

About this Item

This item is printed on demand - Print on Demand Titel. Neuware -Analysis of multidirectional immunological responses at the tumor site allows forming a new concept of The Tumor Immunoenvironment, which is introduced and discussed in the present book with a particular focus on the role of immune cells in controlling the tumor microenvironment at different stages of cancer development. The main goal of this publication is to provide an overview of the current knowledge on the complex and unique role of the immune system, tumor-associated inflammation and tumor-mediated immunomodulation in cancer progression in a way that allows understanding the logistics of cellular and molecular interactions in the tumor lesions.Springer-Verlag KG, Sachsenplatz 4-6, 1201 Wien 764 pp. Englisch.

Seller Inventory # 9789400762169

Bibliographic Details

• Title: The Tumor Immunoenvironment
• Publisher: Springer, Springer Apr 2013
• Publication Date: 2013
• Language: English
• ISBN 10: 940076216X
• ISBN 13: 9789400762169
• Binding: Buch
• Condition: Neu
• Dimensions: 241W x 160H x 47D millimeters 241 millimeters width by 160 millimeters height by 47 millimeters depth
• Weight: 1297 grams

About this title

Synopsis

Analysis of multidirectional immunological responses at the tumor site allows forming a new concept of The Tumor Immunoenvironment, which is introduced and discussed in the present book with a particular focus on the role of immune cells in controlling the tumor microenvironment at different stages of cancer development. The main goal of this publication is to provide an overview of the current knowledge on the complex and unique role of the immune system, tumor-associated inflammation and tumor-mediated immunomodulation in cancer progression in a way that allows understanding the logistics of cellular and molecular interactions in the tumor lesions.

From the Back Cover

Interaction between malignant cells and their surrounding tissue plays a crucial role in tumor growth, invasiveness and spreading to the distant organs. New findings provide evidence of a principal importance of the immune cells for controlling this interaction and orchestrating multiple events in the tumor microenvironment. The balance between immune cells that support tumor progression and immune cells that sustain tumor-controlling immune surveillance is tightly regulated by various factors originated from both the malignant and non-cancerous cells in the tumor microenvironment. Analysis of multidirectional immunological responses at the tumor site allows forming a new concept of The Tumor ImmunoEnvironment, which is introduced and discussed in the present book with a particular focus on the role of immune cells in controlling the tumor microenvironment at different stages of cancer development. The main goal of this publication is to provide an overview of the current knowledge on the complex and unique role of the immune system, tumor-associated inflammation and tumor-mediated immunomodulation in cancer progression in a way that allows understanding the logistics of cellular and molecular interactions in the tumor lesions. Moreover, it is discussed how these interactions evolve during cancer progression and in response to different kinds of anticancer therapy. It is anticipated that the book will attract many researchers and clinicians in the field of basic and applied tumor immunobiology and open new opportunities for collaborative programs aiming at the development of effective and feasible therapeutic approaches to cancer treatment.