Tumor Metabolome Targeting and Drug Development

Language: English

Published by Springer, 2014

146149544X / 9781461495444

Series: Book 79 of 96 - Cancer Drug Discovery and Development

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Seller: AHA-BUCH GmbH, Einbeck, GermanyAHA-BUCH GmbH

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Druck auf Anfrage Neuware - Printed after ordering - In this volume, the major metabolic alterations identified in cancer and tumor-associated cells are explored, including discussions of former and emerging approaches to drug development in targeting cancer cell metabolism. The metabolic network in cells promotes the generation of both energy and biomass needed for them to grow, divide and differentiate. However, the metabolism of malignant cells generally varies from that of normal cells. These differences provide a platform for the discovery of new approaches to targeting potential vulnerabilities in cancer cells for therapeutic options Some of the significant changes that occur involve ATP production and consumption that modulates the ATP to ADP ratio, hypoxia and the effects of reactive oxygen species on glycolysis, regulation of mitochondrial respiration, induction and suppression of autophagy, and the Warburg effect and 'reverse' Warburg effect--these topics and more are discussed in this volume.…

Seller Inventory # 9781461495444

Title
Tumor Metabolome Targeting and Drug Development
Author
Steven Kanner
Publisher
Springer
Publication year
2014
Condition
Neu
Binding
Buch
Language
English
ISBN 10
146149544X
ISBN 13
9781461495444
Item weight
483 grams
Dimensions
241x160x17 mm
Series
Book 79 of 96: Cancer Drug Discovery and Development

AHA-BUCH GmbH

Einbeck, Germany

5-star seller

AbeBooks seller since August 14, 2006

Shipping rates from Germany to U.S.A.

Item7 to 10 business days5 to 7 business days
First itemUS$ 39.87US$ 51.26
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