Tumor Metabolome Targeting and Drug Development

Language: English

Published by Springer New York, Springer US Jan 2014, 2014

146149544X / 9781461495444

Series: Book 79 of 96 - Cancer Drug Discovery and Development

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Seller: buchversandmimpf2000, Emtmannsberg, BAYE, Germanybuchversandmimpf2000

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This item is printed on demand - Print on Demand Titel. Neuware -In this volume, the major metabolic alterations identified in cancer and tumor-associated cells are explored, including discussions of former and emerging approaches to drug development in targeting cancer cell metabolism.The metabolic network in cells promotes the generation of both energy and biomass needed for them to grow, divide and differentiate. However, the metabolism of malignant cells generally varies from that of normal cells. These differences provide a platform for the discovery of new approaches to targeting potential vulnerabilities in cancer cells for therapeutic options Some of the significant changes that occur involve ATP production and consumption that modulates the ATP to ADP ratio, hypoxia and the effects of reactive oxygen species on glycolysis, regulation of mitochondrial respiration, induction and suppression of autophagy, and the Warburg effect and ¿reverse¿ Warburg effect--these topics and more are discussed in this volume.Springer-Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 208 pp. Englisch.…

Seller Inventory # 9781461495444

Title
Tumor Metabolome Targeting and Drug Development
Author
Steven Kanner
Publisher
Springer New York, Springer US Jan 2014
Publication year
2014
Condition
Neu
Binding
Buch
Language
English
ISBN 10
146149544X
ISBN 13
9781461495444
Item weight
483 grams
Dimensions
241x160x17 mm
Series
Book 79 of 96: Cancer Drug Discovery and Development

buchversandmimpf2000

Emtmannsberg, BAYE, Germany

5-star seller

AbeBooks seller since January 23, 2017

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