Tumor Profiling: Methods and Protocols (Methods in Molecular Biology (1908), Band 1908)

Sarah S. Murray

ISBN 10: 1493990020 / ISBN 13: 9781493990023

Published by Humana, 2019

About this Item

Gebraucht - Sehr gut - ungelesen,als Mängelexemplar gekennzeichnet, mit leichten Mängeln an Schnitt oder Umschlag durch Lager- oder Transportschaden -This book provides a practical guide to current methods for profiling and interpreting genomic alterations in tumors. Chapters detail methods to interrogate DNA variation, RNA expression, and epigenetic changes using both next-generation sequencing and microarray techniques, common bioinformatics and annotation tools to glean relevant driver genomic events, and different performance characteristics as well as quality metrics necessary for the robust validation of tumor profiling as a diagnostic test for medical laboratories. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.Humana Press in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin 279 pp. Englisch.

Seller Inventory # INF1000214988

Bibliographic Details

• Title: Tumor Profiling: Methods and Protocols (Methods in Molecular Biology (1908), Band 1908)
• Publisher: Humana
• Publication Date: 2019
• Language: English
• ISBN 10: 1493990020
• ISBN 13: 9781493990023
• Binding: Gebundene Ausgabe
• Condition: Sehr gut
• Dust Jacket Condition: Dust Jacket Included
• Dimensions: 261W x 182H x 20D millimeters 261 millimeters width by 182 millimeters height by 20 millimeters depth
• Weight: 753 grams

About this title

Synopsis

This book provides a practical guide to current methods for profiling and interpreting genomic alterations in tumors. Chapters detail methods to interrogate DNA variation, RNA expression, and epigenetic changes using both next-generation sequencing and microarray techniques, common bioinformatics and annotation tools to glean relevant driver genomic events, and different performance characteristics as well as quality metrics necessary for the robust validation of tumor profiling as a diagnostic test for medical laboratories. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.

Authoritative and cutting-edge, Tumor Profiling: Methods and Protocols aims to be a useful resource for learning about technical details, applications, and strengths and limitations of the latest technologies as applied to this increasingly important field.