Tumour Immunobiology : A Practical Approach

Gallagher, G., Rees, R.C., Reynolds, C.W. - Editors

ISBN 10: 019963369X / ISBN 13: 9780199633692

Published by IRL Press at Oxford University Press, Oxford, 1993

About this Item

Light shelfwear to pictorial cover, 414pp w Index. Tight and bright - appears unread. The idea that the immune system may play a role in protecting against malignant disease is not new. Since the earliest days of immunology research, scientists have sought to understand the mechanisms by which the host immune system might recognize cancer cells, and to manipulate these responses for therapeutic gain. It has become clear that the key to immune recognition of tumors lies in the relationship between cells in the microenvironment of the tumor itself. This volume provides a comprehensive collection of techniques for establishing tumor cell lines, testing their immunogenicity, and characterizing the major effector cells, leading to protocols for manipulating antibody and T-cell receptor structure, preparing cytokine-secreting tumor cells and testing the efficiency of these new agents in preventing tumor growth. Researchers in immunology as a whole in addition to those interested in cancer immunology will find this volume to be an invaluable practical resource.

Seller Inventory # 3287

Bibliographic Details

• Title: Tumour Immunobiology : A Practical Approach
• Publisher: IRL Press at Oxford University Press, Oxford
• Publication Date: 1993
• Language: English
• ISBN 10: 019963369X
• ISBN 13: 9780199633692
• Binding: Soft cover
• Condition: Near Fine
• Seller catalogs:
  • Science & Technical

About this title

Synopsis

The idea that the immune system may play a role in protecting against malignant disease is not new. Since the earliest days of immunology research, scientists have sought to understand the mechanisms by which the host immune system might recognize cancer cells, and to manipulate these responses for therapeutic gain. It has become clear that the key to immune recognition of tumors lies in the relationship between cells in the microenvironment of the tumor itself. This volume provides a comprehensive collection of techniques for establishing tumor cell lines, testing their immunogenicity, and characterizing the major effector cells, leading to protocols for manipulating antibody and T-cell receptor structure, preparing cytokine-secreting tumor cells and testing the efficiency of these new agents in preventing tumor growth. Researchers in immunology as a whole in addition to those interested in cancer immunology will find this volume to be an invaluable practical resource.

About the Author

G. Gallagher, University Department of Surgery, Glasgow Royal Infirmary. R. C. Rees, Department of Experimental and Clinical Microbiology, University of Sheffield. C. W. Reynolds, National Cancer Institute, Frederick, Maryland.