UV AND HPLC Method Development and Method Validation of Nevirapine

Tirthankar Choudhury

ISBN 10: 6200218099 / ISBN 13: 9786200218094

Published by LAP LAMBERT Academic Publishing Jun 2019, 2019

About this Item

Neuware -This research work focused on UV and RP-HPLC method and method validation of Nevirapine accurately and economically. UV spectrophotometric method and mehod development for Nevirapine obeyed Beer's law as depicted by linearity of the developed method. A reverse phase HPLC (RP-HPLC) method is described for the determination of nevirapine in tablet dosage forms. Chromatography was carried on an ODS column using a mixture of methanol and water (89:11 v/v) as the mobile phase at a flow rate of 1 mL/min with detection at 284 nm. The method was validated by determining its sensitivity, accuracy and precision. The proposed method is simple, economical, fast, accurate and precise, hence can be applied for routine quality control of nevirapine in bulk and tablet dosage forms.Books on Demand GmbH, Überseering 33, 22297 Hamburg 108 pp. Englisch.

Seller Inventory # 9786200218094

Bibliographic Details

• Title: UV AND HPLC Method Development and Method Validation of Nevirapine
• Publisher: LAP LAMBERT Academic Publishing Jun 2019
• Publication Date: 2019
• Language: English
• ISBN 10: 6200218099
• ISBN 13: 9786200218094
• Binding: Taschenbuch
• Condition: Neu
• Dust Jacket Condition: Dust Jacket Included
• Dimensions: 220W x 150H x 7D millimeters 220 millimeters width by 150 millimeters height by 7 millimeters depth
• Weight: 179 grams

About this title

Synopsis

This research work focused on UV and RP-HPLC method and method validation of Nevirapine accurately and economically. UV spectrophotometric method and mehod development for Nevirapine obeyed Beer's law as depicted by linearity of the developed method. A reverse phase HPLC (RP-HPLC) method is described for the determination of nevirapine in tablet dosage forms. Chromatography was carried on an ODS column using a mixture of methanol and water (89:11 v/v) as the mobile phase at a flow rate of 1 mL/min with detection at 284 nm. The method was validated by determining its sensitivity, accuracy and precision. The proposed method is simple, economical, fast, accurate and precise, hence can be applied for routine quality control of nevirapine in bulk and tablet dosage forms.