Ubiquitin Proteasome System

Matthew Summers

ISBN 10: 1838804900 / ISBN 13: 9781838804909

Published by Intechopen Jun 2019, 2019

About this Item

This item is printed on demand - it takes 3-4 days longer - Neuware -The human ubiquitin proteasome system (UPS) is comprised of nearly 1000 proteins. Although originally identified as a mechanism of protein destruction, the UPS has numerous additional functions and mediates central signaling events in myriad processes involved in both cellular and organismal health and homeostasis. Numerous pathways within the UPS are implicated in disease, ranging from cancer to neurodegenerative diseases such as Parkinson's. The goal of this book is to deliver a collection of synopses of current areas of UPS research that highlights the importance of understanding the biology of the UPS to identify disease-relevant pathways, and the need to elucidate the molecular machinations within the UPS to develop methods for therapeutic modulation of these pathways. 226 pp. Englisch.

Seller Inventory # 9781838804909

Bibliographic Details

• Title: Ubiquitin Proteasome System
• Publisher: Intechopen Jun 2019
• Publication Date: 2019
• Language: English
• ISBN 10: 1838804900
• ISBN 13: 9781838804909
• Binding: Buch
• Condition: Neu
• Dimensions: 266W x 185H x 20D millimeters 266 millimeters width by 185 millimeters height by 20 millimeters depth
• Weight: 706 grams

About this title

Synopsis

The human ubiquitin proteasome system (UPS) is comprised of nearly 1000 proteins. Although originally identified as a mechanism of protein destruction, the UPS has numerous additional functions and mediates central signaling events in myriad processes involved in both cellular and organismal health and homeostasis. Numerous pathways within the UPS are implicated in disease, ranging from cancer to neurodegenerative diseases such as Parkinson's. The goal of this book is to deliver a collection of synopses of current areas of UPS research that highlights the importance of understanding the biology of the UPS to identify disease-relevant pathways, and the need to elucidate the molecular machinations within the UPS to develop methods for therapeutic modulation of these pathways.