Unconventional electron microscopy for molecular structure determination (Advances in structure research by diffraction methods)

W. Hoppe

ISBN 10: 3528081171 / ISBN 13: 9783528081171

Published by Vieweg 1979-01-01, 1979

About this Item

Seller Inventory # 6666-IUK-9783528081171

Bibliographic Details

• Title: Unconventional electron microscopy for molecular structure determination (Advances in structure research by diffraction methods)
• Publisher: Vieweg 1979-01-01
• Publication Date: 1979
• Language: German
• ISBN 10: 3528081171
• ISBN 13: 9783528081171
• Binding: Paperback
• Condition: New

About this title

Synopsis

Generally it is not sufficiently appreciated that electron microscopy is in fact a diffraction method. In essential aspects electron microscopes are more closely related to X-ray diffracto- meters than to light microscopes. In electron microscopes monochromatized radiation and coherent illumination (never used in light microscopy) correspond in X-ray diffractometers to the primary beam with a small divergence. Imaging ina general sense can take place in interference experiments between a primary beam and a scattered beam, or between diffe- rent deflected scattered beams. This leads to the realization of an old dream in diffracto- metry, namely to a general experimental solution of the "phase problem". The most im- pressive analogy, however, concerns the potential of the electron microscope as a tool for structure determination (where the radiation wavelenght is smaller than the atomic distan- ces). It was therefore considered timely to treat this topic in this series. It was a fortunate cioncidence that in 1976 a Workshop on "Unconventional Electron Microscope Methods for the Investigation of Molecular Structures" (sponsored by the European Molecular Biology Organisation, the Deutsche Forschungsgemeinschaft and the Max-Planck-Gesell- schaft) took place, and that most speakers presenting introductory lectures agreed to publish their contributions in an expanded version in this volume. This volume is thus not a symposium report in the usual sense since it contains the majority of these introductory lectures only.