Title: Understanding Amyotrophic Lateral Sclerosis: Causes and Management: Understanding Causes, Managing Care,and Exploring Treatment Advances inAmyotrophic Lateral Sclerosis
Publisher: LAP LAMBERT Academic Publishing
Publication Date: 2025
Language: English
ISBN 10: 6208420326
ISBN 13: 9786208420321
Binding: Soft cover
Condition: New

About this title

Synopsis

Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disorder marked by muscle weakness, atrophy, fasciculations, and spasticity due to motor neuron degeneration. Symptoms progress from focal weakness to difficulties in speaking, swallowing, and breathing, with eventual paralysis. The disease arises from mechanisms such as disrupted RNA metabolism (e.g., TDP-43 and FUS mutations), cytoskeletal and axonal transport defects (e.g., PFN1, TUBA4A mutations), excitotoxicity, and oxidative stress. While incurable, treatments like Riluzole and Edaravone can modestly slow progression, and supportive care—such as non-invasive ventilation, feeding tubes, and physical therapy—helps manage symptoms. Emerging therapies, including gene and RNA-targeted approaches, hold promise for the future.

"About this title" may belong to another edition of this title.

Store Description

We have 20 years experience selling books worldwide! Friendly customer support. Your satisfaction guaranteed!

Visit Seller's Storefront

Seller's business information

Miramar International Services LLC

Sale & Shipping Terms

Terms of Sale

www.californiabooks.com

Shipping Terms

www.californiabooks.com

Shipping rates within U.S.A.

Shipping rates within U.S.A.
Order quantity	3 to 7 business days	2 to 5 business days
First item	US$ 0.00	US$ 12.00

Delivery times are set by sellers and vary by carrier and location. Orders passing through Customs may face delays and buyers are responsible for any associated duties or fees. Sellers may contact you regarding additional charges to cover any increased costs to ship your items.