Ex Vivo Engineering of the Tumor Microenvironment (Cancer Drug Discovery and Development)

ISBN 10: 3319832824 / ISBN 13: 9783319832821

Published by Humana, 2018

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Bibliographic Details

• Title: Ex Vivo Engineering of the Tumor Microenvironment (Cancer Drug Discovery and Development)
• Publisher: Humana
• Publication Date: 2018
• Language: English
• ISBN 10: 3319832824
• ISBN 13: 9783319832821
• Binding: Paperback
• Condition: New
• Book Type: book

About this title

Synopsis

This volume will outline how to recreate the tumor microenvironment, to culture primary tumors without the need for developmental priming factors, and to deliver targeted therapeutics in a manner that recapitulates pharmacokinetics in vivo. Much of what may be learned from this volume will aid in understanding many aspects of the enhanced study of tumor cell biology in a physiologic context, open new avenues for drug screening and biomarker development, and accelerate the preclinical evaluation of novel personalized medicine strategies for patients in real time.

About the Author

Amir R. Aref, PhD, is Instructor, Dana-Farber Cancer Institute, Harvard Medical School.