This volume consolidates the key methods for studying ligand-nucleic acid interactions into a convenient source. Techniques that are examined range from biophysical and chemical approaches to methods rooted in molecular and cell biology.

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"The Methods in Enzymology series represents the gold-standard." (Neuroscience)

"Incomparably useful." (Analytical Biochemistry)

"...including almost every detail from basic theory to sources of equipment and reagents, with timely documentation provided on each page." (Bio/Technology)

"...It should be on the shelves of all libraries in the world as a whole collection." (Chemistry in Industry)

"The appearance of another volume in that excellent series, Methods in Enzymology, is always a cause for appreciation..." (American Society of Microbiology News)

"If we had some way to find the work most often consulted in the laboratory, it could well be...Methods in Enzymology." (Enzymologia)

"A series that has established itself as a definitive reference for biochemists." (Journal of Chromatography)

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