Niranjana was born in south India and moved to northern Virginia with her family as a toddler. Dr. Partha, as her patients fondly know her, graduated from Georgetown University, Medical College of Virginia, and completed residency training at the University of Pittsburgh Presbyterian Hospital. She then served as a professor of internal medicine for twenty years at the University of Cincinnati, where fellow physicians named her one of the "Best Doctors in America" each of her final eight years in clinical practice.
She now lives in the mid-Atlantic region with her husband Dan and dog.