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Protein Misfolding and Disease (Methods in Molecular Biology, 232)
Seller: Books From California, Simi Valley, CA, U.S.A.
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hardcover. Condition: Good. Ex- library copy with stamps and stickers.
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Condition: New. pp. 340.
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Protein Misfolding and Disease: Principles and Protocols (Methods in Molecular Biology, Vol. 232)
Published by Humana Press, Totowa, NJ, 2003
ISBN 10: 1588290654 ISBN 13: 9781588290656
Language: English
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US$ 67.12
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Add to basketCondition: Sehr gut. Zustand: Sehr gut | Seiten: 344 | Sprache: Englisch | Produktart: Bücher.
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Protein Misfolding and Cellular Stress in Disease and Aging: Concepts and Protocols (Methods in Molecular Biology, 648)
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Protein Misfolding and Disease (Methods in Molecular Biology, 232)
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Add to basketPaperback. Condition: Brand New. reprint edition. 330 pages. 10.00x7.01x0.81 inches. In Stock.
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Protein Misfolding and Cellular Stress in Disease and Aging
Published by Humana Press, Humana Press Aug 2016, 2016
ISBN 10: 1493957597 ISBN 13: 9781493957590
Language: English
Seller: buchversandmimpf2000, Emtmannsberg, BAYE, Germany
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Add to basketTaschenbuch. Condition: Neu. Neuware -How and why certain proteins misfold and how this misfolding is linked to many disease processes has become a well-documented topic of study. Protein Misfolding and Cellular Stress in Disease and Aging: Concepts and Protocols moves beyond the basics to emphasize the molecular effects of protein misfolding at a cellular level, to delineate the impacts and cellular reactions that play a role in pathogenetic mechanisms, and to pinpoint possible manipulations and treatment strategies that can counteract, modify, or delay the consequences of misfolding. The volume begins with several concepts and approaches developed in the recent past including a connection to the research field of aging, where protein misfolding diseases have been equated to premature aging processes, and the book¿s coverage continues with detailed descriptions of protocols for relevant experimental approaches. Written in the highly successful Methods in Molecular Biology¿ series format, protocols chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.Authoritative and cutting-edge, Protein Misfolding and Cellular Stress in Disease and Aging: Concepts and Protocols aims to aid researchers in the field, as well as medical professionals and molecular biologists, in shaping and performing research related to this intriguing and vital subject.Humana Press in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin 344 pp. Englisch.
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Protein Misfolding and Cellular Stress in Disease and Aging: Concepts and Protocols (Methods in Molecular Biology, 648)
Seller: Ria Christie Collections, Uxbridge, United Kingdom
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Protein Misfolding and Disease (Methods in Molecular Biology, 232)
Seller: Ria Christie Collections, Uxbridge, United Kingdom
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Protein Misfolding and Cellular Stress in Disease and Aging : Concepts and Protocols
Seller: GreatBookPricesUK, Woodford Green, United Kingdom
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Condition: New. pp. 336.
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Condition: New. pp. 344.
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Protein Misfolding and Disease
Published by Humana Press, Humana Press Jun 2003, 2003
ISBN 10: 1588290654 ISBN 13: 9781588290656
Language: English
Seller: buchversandmimpf2000, Emtmannsberg, BAYE, Germany
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Add to basketBuch. Condition: Neu. Neuware -For decades it has been known that structured conformations are important for the proper functioning of most cellular proteins. However, appreciation that protein folding to the functional conformations as well as the structural maintenance of protein molecules are very complex processes has only emerged during the last ten years. The intimate interplay uncovered by this scientific development led us to realize that perturbations of the protein folding process and disturbances of conformational maintenance are major disease mechanisms. This development has given rise to the concept of conformational diseases and the broader signature of protein folding diseases, comprising diseases in which mutations or environmental stresses may result in a partial misfolding that leads then to alternative conformations capable of disturbing cellular processes. This may happen by self-association (aggregation), as in prion and Alzheimer¿s diseases, or by incorporation of alternatively folded subunits into structural entities, as in collagen diseases. Another possibility is that folding to the native structure is impaired or abolished, resulting in decreased stea- state levels of the correctly folded protein, as is observed in cystic fibrosis and 1-antitrypsin deficiency, as well as in many enzyme deficiencies. In addition, deficiencies of proteins that are engaged in assisting and supervising protein folding (protein quality control) may impair the folding of many other proteins, resulting in pathological phenotypes. Examples of this are the spastic paraplegia attributable to mutations in mitochondrial protease/chaperone complexes.Humana Press in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin 340 pp. Englisch.
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Protein Misfolding and Cellular Stress in Disease and Aging
Published by Humana Press, Humana Press Aug 2010, 2010
ISBN 10: 1607617552 ISBN 13: 9781607617556
Language: English
Seller: buchversandmimpf2000, Emtmannsberg, BAYE, Germany
Seller rating 5 out of 5 stars
US$ 188.81
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Add to basketBuch. Condition: Neu. Neuware -How and why certain proteins misfold and how this misfolding is linked to many disease processes has become a well-documented topic of study. Protein Misfolding and Cellular Stress in Disease and Aging: Concepts and Protocols moves beyond the basics to emphasize the molecular effects of protein misfolding at a cellular level, to delineate the impacts and cellular reactions that play a role in pathogenetic mechanisms, and to pinpoint possible manipulations and treatment strategies that can counteract, modify, or delay the consequences of misfolding. The volume begins with several concepts and approaches developed in the recent past including a connection to the research field of aging, where protein misfolding diseases have been equated to premature aging processes, and the book¿s coverage continues with detailed descriptions of protocols for relevant experimental approaches. Written in the highly successful Methods in Molecular Biology¿ series format, protocols chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.Authoritative and cutting-edge, Protein Misfolding and Cellular Stress in Disease and Aging: Concepts and Protocols aims to aid researchers in the field, as well as medical professionals and molecular biologists, in shaping and performing research related to this intriguing and vital subject.Humana Press in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin 344 pp. Englisch.
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US$ 273.78
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Add to basketHardcover. Condition: Brand New. 330 pages. 10.25x7.00x1.00 inches. In Stock.
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Protein Misfolding and Cellular Stress in Disease and Aging : Concepts and Protocols
Seller: GreatBookPricesUK, Woodford Green, United Kingdom
Seller rating 5 out of 5 stars
US$ 270.72
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US$ 259.85
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Add to basketHardcover. Condition: Like New. Like New. book.
