Crick Watson (25 results)

Bird Study March 2001 The Journal of the British Trust for Ornithology Volume 48 Part 1
J O'Halloran (Editor) / Andrew M Wilson, Juliet A Vickery and Stephen J Browne "Numbers and distribution of Northern Lapwings Vanellus vanellus breeding in England and Wales in 1998" / David Jenkins and Adam Watson "Bird numbers in relation to grazing on a grouse moor from 1957-61 to 1988-98" / Michael P Toms, Numphrey Q P Crick and Colin R Shawyer "The status of breeding Barn Owls Tyto alba in the United Kingdom 1995-97" / Roger Johansen, Robert T Barrett and Torstein Pedersen "Foraging strategies of great Cormorants Phalacrocorax carbo carbo wintering north of the Arctic Circle"
Published by Blackwell Publishers Ltd 2001
- Softcover
- Periodical
Seller: Shore Books, London, United KingdomShore Books
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Soft cover. Condition: Very Good. 128 pages. Illustrated. Andrew M Wilson, Juliet A Vickery and Stephen J Browne "Numbers and distribution of Northern Lapwings Vanellus vanellus breeding in England and Wales in 1998" / David Jenkins and Adam Watson "Bird numbers in relation to grazing on a grouse moor from 1957-61 to 1988-98" /…Michael P Toms, Numphrey Q P Crick and Colin R Shawyer "The status of breeding Barn Owls Tyto alba in the United Kingdom 1995-97" / Roger Johansen, Robert T Barrett and Torstein Pedersen "Foraging strategies of great Cormorants Phalacrocorax carbo carbo wintering north of the Arctic Circle".
More imagesLanguage: English
Published by Stockholm: Imprimerie Royale F. A. Norstedt & Soner 1963
- Softcover
- First Edition
Seller: Meridian Rare Books ABA PBFA, London, , United KingdomMeridian Rare Books ABA PBFA
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Soft cover. Condition: Near Fine. 1st Edition. First edition. 8vo. pp. 187; ports. of nobel prize winners, illusts.; fine in original printed card wrappers. Crick, Watson and Wilkins collectively received the Nobel Prize for Physiology and Medicine for 1962. Their prize speeches are reproduced in the present volume: respectively… 'On the Genetic Code', 'The Involvement of RNA in the Synthesis of Proteins', and 'The Molecular Configuration of Nucleic Acids'. Other winners this year were Max Perutz for work on crystalline proteins, and John Steinbeck for literature.
Published by Atheneum,, New York, 1968
- Hardcover
- First Edition
Seller: Westsider Rare & Used Books Inc., New York, NY, U.S.A.Westsider Rare & Used Books Inc.
Contact seller4-star sellerHardcover with Dust Jacket. First Printing. First printing with the review slip laid in. Blue cloth with light sunning to the top edge, in a near fine dust jacket. 226pps plus index, Red Cloth.
More imagesTwo complete journal issues of Nature, Vol. 171, comprising: (1) No. 4356, 25 April 1953, containing the three papers under the common head-title 'Molecular Structure of Nucleic Acids': WATSON & CRICK, 'A Structure for Deoxyribose Nucleic Acid,' pp. 737-738; WILKINS, STOKES & WILSON, 'Molecular Structure of Deoxypentose Nucleic Acids,' pp. 738-740; and FRANKLIN & GOSLING, 'Molecular Configuration in Sodium Thymonucleate,' pp. 740-741.(2) No. 4361, 30 May 1953, containing WATSON & CRICK, 'Genetical Implications of the Structure of Deoxyribonucleic Acid,' pp. 964-967
WATSON, J. D. & CRICK, F. H. C.; WILKINS, M. H. F., STOKES, A. R. & WILSON, H. R.; FRANKLIN, R. E. & GOSLING, R. G. [WITH:] WATSON, J. D. & CRICK, F. H. C.
Published by Macmillan, London 1953
- Softcover
- First Edition
Seller: SOPHIA RARE BOOKS, Koebenhavn V, , DenmarkSOPHIA RARE BOOKS
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First edition. Discovery of the Double Helix and the Birth of Molecular Biology. First edition, rare, journal issues in the original printed wrappers, of the four papers by which the double-helix structure of deoxyribonucleic acid was announced to the world and its implications for heredity set out. The 25 April 1953 issue of Na…ture carries, under the common head-title 'Molecular Structure of Nucleic Acids,' three successive papers of a little over a page each: the Watson-Crick paper proposing the double helix with antiparallel sugar-phosphate backbones and complementary base-pairing; the Wilkins-Stokes-Wilson paper reporting the X-ray diffraction evidence that the B-form of DNA is helical; and the Franklin-Gosling paper giving the X-ray diffraction evidence that is in fact decisive for the helical structure, including the famous oxygen positions and fibre-diagram symmetry that Watson and Crick had used, in Franklin's absence and without her permission, to arrive at their model. Five weeks later, in the 30 May issue, the Watson-Crick paper 'Genetical Implications of the Structure of Deoxyribonucleic Acid' sets out what the two 1953 issues together amount to: that the sequence of bases along the double helix is the carrier of hereditary information; that the complementary structure of the molecule itself supplies the mechanism by which this information is copied from one generation to the next; and that mutation can be understood, for the first time, as a change at a single, localisable position in the molecule. For this body of work Watson, Crick, and Wilkins received the 1962 Nobel Prize in Physiology or Medicine; Franklin, who had died of ovarian cancer in 1958 at the age of thirty-seven, was not named. The two issues together are listed in One Hundred Books Famous in Medicine as item 99, in Dibner's Heralds of Science as item 200, in Norman as 534, and in Garrison-Morton as 256.3, 256.4, 256.8, 752.1, and 752.7, reflecting the five distinct discoveries it is possible to cite them for. The problem the papers solved had been on the agenda of biology for eighty-four years. In 1869 the Swiss physiological chemist Friedrich Miescher, working in Felix Hoppe-Seyler's laboratory at Tübingen, had extracted from the nuclei of pus-coated surgical bandages a substance of unprecedentedly high phosphorus content, resistant to the proteolytic enzymes of the day, which he had named 'nuclein.' Miescher and his successors had correctly predicted that a whole family of such phosphorus-rich substances would be found to exist, equivalent in rank to the proteins, but the physiological role of the nucleins had remained unknown for the rest of the century. In 1944 Oswald Avery, Colin MacLeod, and Maclyn McCarty, at the Rockefeller Institute, had established through the pneumococcal transformation experiment that the hereditary material of the cell-the 'transforming principle'-was not, as most biochemists had expected, a protein but was Miescher's nuclein, now understood chemically as deoxyribonucleic acid. Through the following decade the basic chemistry of DNA was worked out: Alexander Todd at Cambridge had established the phosphate-sugar backbone; Erwin Chargaff at Columbia had discovered, from 1950 onward, that in DNA preparations from any source the molar ratio of adenine to thymine and of guanine to cytosine is always one to one, though the A+T to G+C ratio varies between species. These were the data. But what arrangement of atoms produced them, and how the arrangement could act as the carrier of hereditary information through the generations, remained entirely obscure. Two groups in England were applying X-ray crystallographic methods to DNA by the start of 1951. At the Medical Research Council Biophysics Unit at King's College London, under Sir John Randall, Maurice Wilkins had initiated a programme of X-ray diffraction work on DNA fibres; he was joined in late 1950 by Raymond Gosling, then a graduate student, and in January 1951 by Rosalind Franklin, a physical chemist with substantial experience of X-ray crystallography obtained in Paris. The working relationship between Franklin and Wilkins broke down almost at once over a misunderstanding about responsibilities-Randall had verbally placed the DNA work in Franklin's hands without informing Wilkins, who continued to believe it his-and Franklin, with Gosling, worked largely independently through 1951 and 1952. In May 1952 Gosling took, from a well-hydrated fibre of the B-form of DNA that Franklin had prepared, the X-ray photograph that is item 51 in Franklin's laboratory notebook and that is now among the best-known images in the history of science; it shows, from the central cross of spots and the pattern of absences on the layer lines, that the B-form of DNA is an antiparallel double helix with ten residues per turn. By the winter of 1952-1953 Franklin had deduced the space group, the helical parameters, and the antiparallel disposition of the two chains. The one feature she had not yet determined was the base-pairing. At the Cavendish Laboratory in Cambridge, twenty-two-year-old Francis Crick had returned to graduate study in 1949 after the war and was applying the helical diffraction theory of Cochran, Crick, and Vand (1952) to a variety of structural problems; the twenty-three-year-old American James Watson arrived at the Cavendish in October 1951 from a postdoctoral position in Copenhagen with the explicit personal intention of solving the structure of DNA. The two met, agreed that the structure was the central problem of biology, and set out to solve it by the model-building method Linus Pauling had developed for protein ?-helices in 1951. Neither Watson nor Crick was formally assigned to DNA, which was King's territory under an informal British inter-laboratory convention; they nevertheless pursued the problem on and off through 1951 and 1952, producing in late 1951 a disastrously wrong three-stranded model with the phosphate backbones on the inside that Fr.
More imagesMolecular Structure of Nucleic Acids: 'A Structure for Deoxyribose Nucleic Acid', 'Molecular Structure of Deoxypentose Nucleic Acids', and 'Molecular Configuration in Sodium Thymonucleate' in Nature volume 171, number 4356, pp. 737-738. 'Genetical Implications of the Structure of Deoxyribonucleic Acid' in number 4361, pp. 964-967.
CRICK, Francis; WATSON, James; WILKINS, Maurice; FRANKLIN, Rosalind.
Published by London Macmillan and Co. Ltd 1953
- Softcover
- First Edition
Seller: Shapero Rare Books, London, United KingdomShapero Rare Books
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First edition, complete volume, signed by Crick on the first paper; 8vo (24.5 x 17 cm); illustrations throughout the text, 1982 ownership inscription of J.D. Mollon to front pastedown, spotting to early and late leaves; contemporary green library cloth, titles to spine gilt, red speckled edges, corners bumped and worn, a little…wear at the ends of the spine, lower joint just starting, very good condition; 1168pp, 64 page index. First edition, the complete journal volume containing the first four papers on the structure of DNA, signed by Crick on the 'Molecular Structure of Nucleic Acids' paper. From the library of John D. Mollon, eminent professor of visual neuroscience at Cambridge.
More images[Breakthroughs in genetics, signed by Crick] Nature: A Weekly Journal of Science. Vol. 171 (January 3, 1953 to June 27, 1953), Vol. 172 (July 4, 1953 to December 26, 1953), Vol. 192 (October 7, 1961 to December 30, 1961)
Francis Crick & Rosalind Elsie Franklin & James D. Watson & Maurice Hugh Wilkins
Published by Francis Crick & Rosalind Elsie Franklin & James D. Watson & Maurice Hugh Wilkins 1953
- Hardcover
Seller: Barry Lawrence Ruderman, La Jolla, CA, U.S.A.Barry Lawrence Ruderman
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Hardcover. Condition: VG+. Volume 171 J.D.Watson and F.H.C. Crick, "Molecular Structure of Nucleic Acids A Structure for Deoxyribose Nucleic Acid", 737 J.D.Watson and F.H.C. Crick, "Genetical Implications of the Structure of Deoxyribonuclei. Quarto. Three volumes, each bound in blue cloth with label to spine. Occasional f…ingersoiling and pencil marginalia. Light foxing to block edges of Vol. 172. Vol. 171 with inked and embossed stamps of Naval Research Laboratory Library to title page. Tape repair to 1181/82 of Vol. 172. Signed by Crick at first page of each of three articles he co-authored (twice in Vol. 171, once in Vol. 192). Housed in blue cloth slipcase. Vol. 171: [ii], 1168, iii-llxiv. Vol. 172: lxxi, [1], 1200 pp. Vol. 192: cvii, [cviii, blank], xiv-xvi, 50, xvii-xxx, 51-70, xxxi-xxxii, 71-94, lxi-lxiv, 95-112, lxv-lxxx, 113-194, cvii-cxxii, 195-292, clv-clxxii, 293-372, clxxii-clxxiv, 373-386, cciii-ccxxii, 387-484, ccxlvii-cclxv, 485-586, cclxxxix-cccviii, 587-688, cccxxxiii-cccl, 689-784, ccclxxxi-ccccxviii, 785-989, ccccxli-ccccxlviii, 899-1002, cccclxxxiii-dii, 1003-1104, dxxi-dxxxii, 1105-1218, dliii-dlxxii, 1219-1322 Volume 171 J.D.Watson and F.H.C. Crick, "Molecular Structure of Nucleic Acids A Structure for Deoxyribose Nucleic Acid", 737 J.D.Watson and F.H.C. Crick, "Genetical Implications of the Structure of Deoxyribonucleic Acid", 964 Rosalind E. Franklin and R. G. Gosling, "Molecular Structure of Nucleic Acids Molecular Configuration in Sodium Thrymonucleate", 740 M.H.F. Wilkins, A.R. Stokes & H.R. Wilson, "Molecular Structure of Deoxypentose Nucleic Acids", 738 Volume 172 Rosalind E. Franklin and R. G. Gosling, "Evidence for 2-Chain Helix in Crystalline Structure of Sodium Deoxyribonucleate", 156 M.H.F. Wilkins, W.E. Seeds & A. R. Stokes, H.R. Wilson, "Helical Structure of Crystalline Deoxypentose Nucleic Acid", 759 Volume 192 F.H.C. Crick, Leslie Barnett, S. Brenner, R.J. Watts-Tobin, "General Nature of the Genetic Code for Proteins", 1227. Book.

Published by J. & A. Churchill, London 1957
- Hardcover
- First Edition
- Signed
Seller: Raptis Rare Books, Palm Beach, FL, U.S.A.Raptis Rare Books
Contact seller5-star sellerFirst edition of Watson and Crickâs classic work on Virus Structure. Octavo, original cloth. Boldly signed by James Watson on the front free endpaper. Fine in a very good dust jacket. Rare and desirable signed. Presented as the first paper at the prestigious 1956 Ciba Foundation. symposium and the first paper in this collection,… this seminal workâ" their "last direct collaboration" (Ridley)â"revealed Watson and Crickâs theory of virus structure, a "great success" (Judson, 316).

Published by Walker and Company, New York 1994
- Hardcover
- First Edition
- Signed
Seller: Raptis Rare Books, Palm Beach, FL, U.S.A.Raptis Rare Books
Contact seller5-star sellerFirst edition of this riveting work on the legendary scientist James D. Watson. Octavo, original boards. Boldly signed by James Watson and Francis Crick on the half-title page. Fine in a fine dust jacket. Jacket design by Ron Monteleone. Rare and desirable signed by Watson and Crick. In its drama, Watson's life has rivaled the d…iscovery of the structure of DNA. So intent on his research was this awkward, bumbling scholar that he would climb a drainpipe to sneak into a lab at night. Watson had a knack for selecting problems that would yield important scientific results, but did he pilfer? Did Rosalind Franklin originate crucial material? If so, why was she not included in the Nobel Prize? Baldwin, who had exceptional access to Watson and his family, conveys the elegance of science (the ``structure [of DNA] was too pretty not to be true''), describes diverse influences (birding, Arrowsmith, movies), and even gives advice (go to a college where others are brighter than you, to test your mettle). Voluminous detail on what, exactly, provided a lifetime's worth of inspiration broaden an intriguing picture of this intrepid competitor.
More imagesPublished by Atheneum, New York 1968
- Hardcover
- First Edition
- Signed
Seller: Raptis Rare Books, Palm Beach, FL, U.S.A.Raptis Rare Books
Contact seller5-star sellerFirst edition of Watson's ground breaking work regarding the discovery of DNA for which the author, Francis Crick and Maurice Wilkins were awarded the Nobel Prize in Medicine in 1962. Signed by both James Watson and Francis Crick on the title page. Lengthily signed with a quote written by Watson on the half-title page, "I think…people are born curious and too often have it pounded out of their spirit." Octavo, original blue cloth, with numerous diagrams and photographic illustrations. Fine in a fine dust jacket. Jacket design by Jeanyee Wong. Foreword by Sir Lawrence Bragg. ÂHoused in a custom half morocco clamshell box by the Harcourt Bindery. A unique example, most rare and desirable with a lengthy quote from the co-discover of DNA. "Science seldom proceeds in the straightforward logical manner imagined by outsiders," writes James Watson in The Double Helix, his account of his codiscovery (along with Francis Crick) of the structure of DNA. Watson, Crick and Maurice Wilkins won Nobel Prizes for their work, and their names are memorized by biology students around the world. But as in all of history, the real story behind the deceptively simple outcome was messy, intense, and sometimes truly hilarious. To preserve the "real" story for the world, James Watson attempted to record his first impressions as soon after the events of 1951-1953 as possible, with all their unpleasant realities and "spirit of adventure" intact. "One of the investigators, more than any of the others, realized the decisive importance of the DNA molecules in biology, and it was this understanding which urged him relentlessly to push this work toward a successful conclusion, in spite of his rather modest technical qualifications for this task" (Mayr, 823). "He has described admirably how it feels to have that frightening and beautiful experience of making a great scientific discovery" (Richard Feynman, winner of the 1965 Nobel Prize for Physics).
More imagesPublished by London: Weidenfeld & Nicolson, 1968. 1968
- Hardcover
- Signed
Seller: Scientia Books, ABAA ILAB, Arlington, MA, U.S.A.Scientia Books, ABAA ILAB
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Hardcover. Condition: Very Good. Dust Jacket Included. 1 leaf, xvi, 226 pp; illus. Original cloth. Swedish postage stamp honoring Crick, Watson, and Wilkins for the Nobel Prize in 1962 is pasted to title page. Wilkins's inscription is partly on the stamp. Very Good, in dust jacket. Third Impression of British Edition. The follow…ing pages are signed or annotated: 1. Title page: SIGNED BY NOBEL LAUREATES JAMES D. WATSON, FRANCIS CRICK, MAURICE WILKINS ("with best wishes/ Maurice Wilkins/ April 2003"), AND BY RAYMOND GOSLING. 2. p. 214: SIGNED BY FRANCIS CRICK AND JAMES D. WATSON UNDER THE PHOTOGRAPH SHOWING THEM STANDING BY THEIR DNA MODEL (opposite p. 214). 3. p. 18 SIGNED BY MAURICE WILKINS UNDER HIS PHOTOGRAPH (opposite p. 18). 4. Annotated by Raymond G. Gosling about Rosalind Franklin (under her photograph opposite p. 70): "She had wonderfully lustrous dark eyes. I found her very attractive, as did most everyone who worked with her. She had a strong personality and did not suffer fools gladly. Her powers of concentration were quite fierce and she could get done in a day what other people might have taken several to achieve. Raymond Gosling Sept. 2003". 5. Annotated by Raymond G. Gosling about X-ray photograph of crystalline DNA in the A form (under photograph opposite p. 72): "The pattern that 'kick started' the whole story. A multifibre (about 35) specimen made by Wilkins & myself and taken on a conventional Rayniax tube in the basement of King s College London. This pattern was one shewn by Maurice at the Naples meeting. The A form was obtained serendipitously by my regulating the Hydrogen into the camera by bubbling thru' water--hence ~92% RH. Raymond Gosling. Sept. 2003." 6. Annotated by Raymond G. Gosling about X-ray photograph of DNA in the B form, taken by Rosalind Franklin late in 1952 (under photograph opposite p. 169): "As Rosalind's assistant I actually 'took' this X-ray pattern. Since we were working closely together the overall strategy was Rosalind's. Therefore the importance attributed to some--as to who 'took' the photograph--is inappropriate. R G Gosling Sept. 2003." NOTE: I have included photos of everything signed or annotated, except for Maurice Wilkins's signature under his photo (opposite p. 18). I have a photo of that signature, too, which I will supply on request, but ABE allows only 5 photos per listing. Signed by Author(s).
More imagesNeurobiology of the Leech. SIGNED BY JAMES WATSON TO FRANCIS CRICK (twice and differently).
[WATSON, James D.] [CRICK, Francis] MULLER, Kenneth J.; John G. NICHOLLS & Gunther S. STENT(eds.)
Published by Cold Spring Harbor Laboratory, 1981. 1981
- Hardcover
- First Edition
- Signed
Seller: Scientia Books, ABAA ILAB, Arlington, MA, U.S.A.Scientia Books, ABAA ILAB
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Hardcover. Condition: Very Good. 1st Edition. x, 320 pp; illus. Original laminated boards. Spine worn, else Very Good. First Edition. SIGNED, TWICE (AND DIFFERENTLY), BY JAMES WATSON TO FRANCIS CRICK. In back, upside down, on the rear flyleaf, Watson has written: "for Francis with the faint hope/ that he will abandon the vertebr…ate brain/ Jim/ Kyoto ___?/ December 1981". In front on the front flyleaf, Watson has written: "for Francis/ with the mild? hope that/ you might realize that vision and vertebrates/ might be biting off too much/ Jim/ Kyoto ___?/ 1981". With the ink name stamp "Prof. F. H. C. Crick" on the front flyleaf. Acknowledgment of the editors (p. vii): "We thank James D. Watson for proposing the idea of this book to us; year by year, his unfailing support and enthusiasm for the leech neurobiology course has provided an opportunity for contact among investigators working on the leech, for exchanging ideas and jointly developing new techniques.". Signed by Author(s).
More imagesNobel Lectures: Physiology or Medicine 1942-1962.
Watson, James D; Francis Crick; Maurice Wilkins; Arthur Kornberg, Joshua Lederberg
Published by Elsevier Publishing Company, Amsterdam 1964
- Hardcover
- First Edition
- Signed
Seller: Raptis Rare Books, Palm Beach, FL, U.S.A.Raptis Rare Books
Contact seller5-star sellerFirst edition of this collection of Nobel Lectures in physiology or medicine from the years 1942-1962. Thick Octavo, original yellow cloth. Signed by all three Nobel Prize-winning scientists Francis Crick, James D. Watson and Maurice Wilkins on the title page. They were awarded the Nobel Prize in Medicine in 1962, "for their dis…coveries concerning the molecular structure of nucleic acids and its significance for information transfer in living material."Fine in a very good dust jacket with some closed tears and toning to the spine. An exceptional piece signed by these Nobel Prize-winning scientists. In the early 1950s, the race to discover DNA was on. At Cambridge University, graduate student Francis Crick and research fellow James Watson had become interested, impressed especially by Pauling's work. Meanwhile at King's College in London, Maurice Wilkins (b. 1916) and Rosalind Franklin were also studying DNA. The Cambridge team's approach was to make physical models to narrow down the possibilities and eventually create an accurate picture of the molecule. The King's team took an experimental approach, looking particularly at x-ray diffraction images of DNA. Watson and Crick took a crucial conceptual step, suggesting the molecule was made of two chains of nucleotides, each in a helix as Franklin had found, but one going up and the other going down. Crick had just learned of Chargaff's findings about base pairs in the summer of 1952. He added that to the model, so that matching base pairs interlocked in the middle of the double helix to keep the distance between the chains constant. Watson and Crick showed that each strand of the DNA molecule was a template for the other. During cell division the two strands separate and on each strand a new "other half" is built, just like the one before. This way DNA can reproduce itself without changing its structure -- except for occasional errors, or mutations. The structure so perfectly fit the experimental data that it was almost immediately accepted. DNA's discovery has been called the most important biological work of the last 100 years, and the field it opened may be the scientific frontier for the next 100.

Published by Cold Spring Harbor Laboratory, Cold Spring, NY 1987
- Hardcover
- First Edition
- Signed
Seller: Raptis Rare Books, Palm Beach, FL, U.S.A.Raptis Rare Books
Contact seller5-star sellerFirst edition of the collected speeches of the 52nd Cold Spring Harbor Symposia on Quantitative Biology. Foreword by James D. Watson. Quarto, original red cloth, illustrated with photographs, diagrams. Association copy, inscribed by James Watson to Francis Crick on the front free endpaper, "For Francis, the first of us to think…sensibly as to what the Central Dogma tells us about the origin of life, from Jim, upon the 35th anniversary of the Double Helix. April 10, 1988." Also signed by Francis Crick. A unique piece of history between arguably the two most influential scientists of the twentieth century, co-discoverers of the structure of DNA. In near fine condition. Housed in a custom slipcase. An exceptional association linking the discoverers of the molecular structure of DNA. Participants of the 52nd Symposia on Quantitative Biology included James D. Watson, James Darnell, Peter Moore, Raul Saavedra, and Fusao Tomita, each of whom spoke on a wide range of topics related to the discovery, structure and informational properties of RNA. Watson made his first trip to Cold Spring Harbor in 1948 at the age of 20, he returned 5 years later to make his seminal presentation reporting the discovery of DNA, for which he and Francis Crick would be awarded the Nobel Prize. Watson's "second act" commenced in 1968, when, following the publication of The Double Helix, he became the laboratory's Director. During his tenure, he transformed CSHL from an institution suffering from a lack of funding into one of the world's primary biomedical research centers.

Published by Weidenfeld & Nicolson, London 1968
- Hardcover
- First Edition
- Signed
Seller: Raptis Rare Books, Palm Beach, FL, U.S.A.Raptis Rare Books
Contact seller5-star sellerFirst edition of Watson's ground breaking work regarding the discovery of DNA for which the author, Francis Crick and Maurice Wilkins were awarded the Nobel Prize in Medicine in 1962.ÂOctavo, original cloth, illustrated with 19 half-tone illustrations and 11 diagrams. Signed by both James D. Watson and Francis Crick on the title… page. Very good in an excellent dust jacket with some light rubbing to the spine crown. Jacket design by Dorothy Judd. Foreword by Sir Lawrence Bragg. Rare signed by both Watson and Crick. "Science seldom proceeds in the straightforward logical manner imagined by outsiders," writes James Watson in The Double Helix, his account of his codiscovery (along with Francis Crick) of the structure of DNA. Watson, Crick and Maurice Wilkins won Nobel Prizes for their work, and their names are memorized by biology students around the world. But as in all of history, the real story behind the deceptively simple outcome was messy, intense, and sometimes truly hilarious. To preserve the "real" story for the world, James Watson attempted to record his first impressions as soon after the events of 1951-1953 as possible, with all their unpleasant realities and "spirit of adventure" intact. "One of the investigators, more than any of the others, realized the decisive importance of the DNA molecules in biology, and it was this understanding which urged him relentlessly to push this work toward a successful conclusion, in spite of his rather modest technical qualifications for this task" (Mayr, 823). "He has described admirably how it feels to have that frightening and beautiful experience of making a great scientific discovery" (Richard Feynman, winner of the 1965 Nobel Prize for Physics).
More imagesPublished by 2002. 2002
- Softcover
- Signed
- Manuscript
Seller: Scientia Books, ABAA ILAB, Arlington, MA, U.S.A.Scientia Books, ABAA ILAB
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Soft cover. Condition: Very Good. 2 leaves, 364 pp (printed on both sides of each page). Spiral-bound. The front cover is a clear plastic. The rear cover is a black paper. Very Good. SIGNED BY JAMES WATSON TO FRANCIS CRICK: "For Francis/ from/ Jim/ 17 January 2003." (see photos) "Copyright 2002 by J. D. Watson. Not to be reprint…ed without permission.". Signed by Author(s).
Ciba Foundation Symposium on the Nature of Viruses
(Crick, Francis & J.D. Watson) Wolstenholme, G. E. W., editor
Published by Churchill, London 1957
- First Edition
Seller: The Old Mill Bookshop, HACKETTSTOWN, NJ, U.S.A.The Old Mill Bookshop
Contact seller3-star sellerxii, 292pp. 8vo. Condition: Green cloth. Fine. First Edition. First Edition. xii, 292pp. 8vo. Crick and Watson's article is the first in this collection "Virus Structure: General Principles" at pp.5-13.
More imagesMolecular Structure of Nucleic Acids: A Structure for Deoxyribose Nucleic Acid; Molecular Structure of Deoxypentose Nucleic Acids; Molecular Configuration in Sodium Thymonucleate; Three papers from Nature, Vol. 171, No. 4356, April 25, 1953
Watson, J. D.; Crick, F. H. C.; Wilkins, M. H. F., Stokes, A. R. & Wilson, H. R.; Franklin, R. E. & Gosling, R. G.
Published by Fisher, Knight & Co, St. Albans 1953
- First Edition
- Signed
Seller: Biblioctopus, Los Angeles, CA, U.S.A.Biblioctopus
Contact seller4-star sellerFirst Edition. Offprint, 8vo (210 x 140mm), pp. 14, with two diagrams (including the double helix) and two illustrations from photographs. The three-paper offprint issue, of the primary record of the co-discovery of the molecular structure of DNA, the most transformative moment in twentieth-century biology. Stapled in self-wrapp…ers as issued. Signed by Maurice Wilkins on the first page. Very lightly toned and a coulpe soft creases, near fine. Grolier Club, One Hundred Books Famous in Medicine, 99; Dibner, Heralds of Science, 200. Garrison-Morton 256.3; Judson, Eighth Day of Creation, pp. 145-56. Ex-Dr. Myron Printzmetal. The discovery of DNA's double helix structure emerged from an intense period of competitive collaboration between research teams at Cambridge and King's College London. Watson and Crick's theoretical breakthrough synthesized crucial experimental evidence from multiple sources: Erwin Chargaff's base composition rules demonstrating the 1:1 ratio of adenine to thymine and guanine to cytosine, X-ray crystallographic data revealing DNA's helical structure, and most critically, the precise measurements of backbone positioning and molecular dimensions. Their elegant model proposed complementary base pairing (A-T and C-G) held together by hydrogen bonds, immediately suggesting a mechanism for genetic replication where each strand could serve as a template for its complement. The accompanying papers by Wilkins, Stokes, and Wilson, and by Franklin and Gosling, provided essential experimental validation through X-ray diffraction analysis, creating a unified presentation of both theoretical insight and empirical evidence that established the foundation of molecular biology. The contentious history surrounding this discovery has generated enduring scholarly debate, particularly regarding the systematic marginalization of Rosalind Franklin's contributions. Franklin's meticulous X-ray crystallographic work, conducted with her graduate student Raymond Gosling, had independently determined many key structural features including the antiparallel orientation of DNA strands, the external positioning of phosphate groups, and precise helical parameters. Her famous "Photograph 51" provided definitive evidence of DNA's helical structure, while her systematic analysis of A-form and B-form DNA revealed critical dimensions that enabled Watson and Crick's model construction. As Brenda Maddox documents in "Rosalind Franklin: The Dark Lady of DNA," Franklin's data was shown to Watson and Crick without her knowledge through Maurice Wilkins, creating an ethical controversy that persists in discussions of scientific collaboration and gender bias. Franklin's death from ovarian cancer in 1958, four years before the Nobel Prize was awarded to Watson, Crick, and Wilkins, has intensified debates about recognition and the complex dynamics of mid-twentieth century scientific discovery, with many scholars arguing that her rigorous experimental approach was as fundamental to the breakthrough as the theoretical modeling that received greater acclaim. This publication represents the founding document of modern molecular biology, establishing the conceptual framework for understanding heredity, genetic replication, and the molecular basis of life itself. The discovery immediately suggested mechanisms for protein synthesis and genetic information transfer, creating the theoretical foundation for subsequent developments in genetic engineering, biotechnology, and genomic medicine. As Francis Crick later observed, the structure's elegant simplicitywith its complementary base pairing and antiparallel strandsprovided not merely a static model but a dynamic mechanism explaining how genetic information could be accurately copied and transmitted across generations. The offprint's scientific significance extends far beyond its immediate discovery, representing the moment when biology transformed from a primarily descriptive science into a molecular discipline capable of manipu.
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Soft cover. Condition: Near Fine. THE DISCOVERY OF THE STRUCTURE OF DNA, the cornerstone event in modern genetics and biology and one of the greatest scientific discoveries of all time. Signed by Francis Crick. This is the original announcement of the discovery of the double helix structure of DNA. It is accompanied by two impor…tant related papers on DNA, one by Wilkins, Stokes and Wilson, the other by Franklin and Gosling. In 1962 Watson, Crick, and Maurice Wilkins shared the Nobel Prize for medicine. It is very unusual to see this great paper in original state, as most of those that survive are now in bound volumes. Watson and Crick conclude the first paper with a classic understatement: The structure has novel features which are of considerable biological interest. . . . It has not escaped our notice that the specific pairing we have postulated immediately suggests a possible copying mechanism for the genetic material. In 1962 Watson, Crick, and Maurice Wilkins shared the Nobel Prize for medicine. Offprint from: Nature 171, no. 4356 (April 25, 1953), 737-38. Original wrappers. Some foxing. Very good. Signed by Author(s).
More images'Molecular Structure of Nucleic Acids: A Structure for Deoxyribose Nucleic Acid'; 'Molecular Structure of Deoxypentose Nucleic Acids'; 'Molecular Configuration in Sodium Thymonucleate'. Three papers in a single offprint from Nature, Vol. 171, No. 4356, April 25, 1953
WATSON, J. D. & CRICK, F. H. C.; WILKINS, M. H. F., STOKES, A. R. & WILSON, H. R.; FRANKLIN, R. E. & GOSLING, R. G.
Published by Fisher, Knight & Co, St. Albans 1953
- First Edition
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First edition. DISCOVERY OF THE STRUCTURE OF DNA. First edition, in the rare offprint form, of one of the most important scientific papers of the twentieth century, which "records the discovery of the molecular structure of deoxyribonucleic acid (DNA), the main component of chromosomes and the material that transfers genetic cha…racteristics in all life forms. Publication of this paper initiated the science of molecular biology. Forty years after Watson and Crick's discovery, so much of the basic understanding of medicine and disease has advanced to the molecular level that their paper may be considered the most significant single contribution to biology and medicine in the twentieth century" (One Hundred Books Famous in Medicine, p. 362). "The discovery in 1953 of the double helix, the twisted-ladder structure of deoxyribonucleic acid (DNA), by James Watson and Francis Crick marked a milestone in the history of science and gave rise to modern molecular biology, which is largely concerned with understanding how genes control the chemical processes within cells. In short order, their discovery yielded ground-breaking insights into the genetic code and protein synthesis. During the 1970s and 1980s, it helped to produce new and powerful scientific techniques, specifically recombinant DNA research, genetic engineering, rapid gene sequencing, and monoclonal antibodies, techniques on which today's multi-billion dollar biotechnology industry is founded. Major current advances in science, namely genetic fingerprinting and modern forensics, the mapping of the human genome, and the promise, yet unfulfilled, of gene therapy, all have their origins in Watson and Crick's inspired work. The double helix has not only reshaped biology, it has become a cultural icon, represented in sculpture, visual art, jewelry, and toys" (Francis Crick Papers, National Library of Medicine, profiles./SC/Views/Exhibit/narrative/). In 1962, Watson, Crick, and Wilkins shared the Nobel Prize in Physiology or Medicine "for their discoveries concerning the molecular structure of nucleic acids and its significance for information transfer in living material." In 1869, the Swiss physiological chemist Friedrich Miescher (1844-95) first identified what he called 'nuclein' inside the nuclei of human white blood cells. (The term 'nuclein' was later changed to 'nucleic acid' and eventually to 'deoxyribonucleic acid,' or 'DNA.') Miescher's plan was to isolate and characterize not the nuclein (which nobody at that time realized existed) but instead the protein components of leukocytes (white blood cells). Miescher thus made arrangements for a local surgical clinic to send him used, pus-coated patient bandages; once he received the bandages, he planned to wash them, filter out the leukocytes, and extract and identify the various proteins within the white blood cells. But when he came across a substance from the cell nuclei that had chemical properties unlike any protein, including a much higher phosphorous content and resistance to proteolysis (protein digestion), Miescher realized that he had discovered a new substance. Sensing the importance of his findings, Miescher wrote, "It seems probable to me that a whole family of such slightly varying phosphorous-containing substances will appear, as a group of nucleins, equivalent to proteins". But Miescher's discovery of nucleic acids was not appreciated by the scientific community, and his name had fallen into obscurity by the 20th century. "Researchers working on DNA in the early 1950s used the term 'gene' to mean the smallest unit of genetic information, but they did not know what a gene actually looked like structurally and chemically, or how it was copied, with very few errors, generation after generation. In 1944, Oswald Avery had shown that DNA was the 'transforming principle,' the carrier of hereditary information, in pneumococcal bacteria. Nevertheless, many scientists continued to believe that DNA had a structure too uniform and simple to store genetic information for making complex living organisms. The genetic material, they reasoned, must consist of proteins, much more diverse and intricate molecules known to perform a multitude of biological functions in the cell. "Crick and Watson recognized, at an early stage in their careers, that gaining a detailed knowledge of the three-dimensional configuration of the gene was the central problem in molecular biology. Without such knowledge, heredity and reproduction could not be understood. They seized on this problem during their very first encounter, in the summer of 1951, and pursued it with single-minded focus over the course of the next eighteen months. This meant taking on the arduous intellectual task of immersing themselves in all the fields of science involved: genetics, biochemistry, chemistry, physical chemistry, and X-ray crystallography. Drawing on the experimental results of others (they conducted no DNA experiments of their own), taking advantage of their complementary scientific backgrounds in physics and X-ray crystallography (Crick) and viral and bacterial genetics (Watson), and relying on their brilliant intuition, persistence, and luck, the two showed that DNA had a structure sufficiently complex and yet elegantly simple enough to be the master molecule of life. "Other researchers had made important but seemingly unconnected findings about the composition of DNA; it fell to Watson and Crick to unify these disparate findings into a coherent theory of genetic transfer. The organic chemist Alexander Todd had determined that the backbone of the DNA molecule contained repeating phosphate and deoxyribose sugar groups. The biochemist Erwin Chargaff had found that while the amount of DNA and of its four types of bases - the purine bases adenine (A) and guanine (G), and the pyrimidine bases cytosine (C) and thymine (T) - varied widely from species to species, A and T always appeared in ratios of one-to-one, as did G and C. Maurice Wilkins an.
More imagesMolecular Structure of Nucleic Acids. Reprinted from Nature, Vol. 171, p. 737, April 25, 1953.
CRICK, Francis; Rosalind Franklin; James Watson; Maurice Wilkins.
Published by St Albans: Fisher, Knight & Co., Ltd, 1953 1953
- First Edition
Seller: Peter Harrington. ABA/ ILAB., London, United KingdomPeter Harrington. ABA/ ILAB.
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First edition, the three-paper offprint issue, of the primary record of the co-discovery of the molecular structure of DNA. This copy is from the library of Professor Hans Gustav Boman (1924-2008), the leading molecular biologist in Sweden; his signature is in ink on the first page. Three research groups independently investigat…ed the structure of DNA in England in the early 1950s: Francis Crick and James Watson at the Cavendish Laboratory in Cambridge and two teams at King's College, London comprising Maurice Wilkins, Rosalind Franklin, Raymond Gosling, Alec Stokes, and Herbert Wilson. To acknowledge the simultaneity of the discovery, the directors of the respective institutions agreed that the three resulting papers would be published under the general title Molecular Structure of Nucleic Acids in the British scientific weekly Nature. Crick and Watson's paper, "A Structure for Deoxyribose Nucleic Acid", is illustrated with a schematic drawing by Odile Crick of the twisted-ladder structure of DNA, now famously known as the double helix. Wilkins, Stokes, and Wilson co-wrote "Molecular Structure of Deoxypentose Nucleic Acids", the second paper. Franklin and her research student Gosling submitted "Molecular Configuration in Sodium Thymonucleate", which features a half-tone illustration of Gosling's iconic X-ray "Photograph 51" of crystallized DNA. Franklin died four years before the Nobel Prize in Physiology or Medicine was awarded to Crick, Watson, and Wilkins in 1962 for their work on DNA, but without question her "contributions, and indeed her actual X-ray data, were crucial to the total achievement" (ODNB). "Two offprints exist of Watson and Crick's paper: a single sheet containing the Watson and Crick article only, and a fourteen-page pamphlet containing the papers of all three research groups. The pamphlet pages are smaller in size than the single leaf, which has the same dimensions as the leaves of the journal, and the layout is different, the single-leaf offprint being printed in two columns like the journal, the pamphlet in single-column pages. The page breaks are different in each of the two offprints and the journal, as is the placement of the illustrations relative to the text. Despite these differences, all three versions appear to have been printed from the same setting of type, except that in the two offprints one paragraph of text has been reset to accommodate the placement of the diagram of the DNA molecule" (Grolier, p. 363). Haskell F. Norman discusses the difficulty in establishing priority between the two formats in his introduction to One Hundred Books Famous in Medicine and closes by stating that "it is now our tentative conclusion that the three-paper offprint is the first issue" (p. xxi). Boman "was one of the pioneers in the field of molecular biology in Sweden" (Norrby, p. 11). After teaching at Uppsala University he transferred to Umeå University to establish their microbiology department; under his leadership it became an international hub of research excellence. "Halfway through his career Boman moved on to Stockholm University and initiated a completely new line of research. It pioneered the development of insights into the emerging field of natural immunity. He developed this work in collaboration with Swedish colleagues and coined the term cecropines for this new kind of peptide antibiotics. This was a Nobel-class discovery" but - like Franklin - Boman died before he could see his research recognized as such (Norrby, p. 11). In 2011, his work formed the basis of a discovery by Jules Hoffman and Bruce Beutler, for which they received the Nobel Prize in Physiology or Medicine. Garrison-Morton 256.3 (Crick and Watson's paper); Grolier, One Hundred Books Famous in Medicine, 99; Heirs of Hippocrates 2342. Erling Norrby, Nobel Prizes: Cancer, Vision and the Genetic Code, 2019. Octavo, pp. 14. With 4 illustrations. Printed pamphlet, wire-stitched as issued. A few neat red pencil marks to first three pages, lower outer corners creased: a near-fine copy.
More imagesNATURE. A Weekly Journal of Science. The six milestone papers on the structure of DNA
WATSON, James D, Francis H.C.Crick, Rosalind Franklin, M.H.F. Wilkins and others
Published by London: Macmillan and Co., Ltd 1953 1953
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Two bound volumes. Volume 171 (January 3 1953 to June 27 1953) and Volume 172 (July 4 1953 to December 22 1953). Bound in maroon (vol. 171) and brick-red (vol. 172) cloth, spine lettered in gilt. In very good condition. Front pastedown has the bookplate of Worthing Public Library and title page of volume 172 (and verso of volume… 171) has a small round Worthing Public Library stamp. The papers are as follows: 1. Molecular Structure of Nucleic Acids: A Structure for Deoxyribose Nucleic Acid, by J.D.Watson and F.H.C. Crick. Nature, Volume 171, No. 4356. April 25 1953. pp737-738. 2. Molecular Structure of Deoxypentose Nucleic Acids, by M.H.F. Wilkins, A.R.Stokes and H.R.Wilson Nature, Volume 171, No. 4356. April 25 1953. pp738-740. 3. Molecular configuration in Sodium Thymonucleate by Rosalind E. Franklin and R.G.Gosling. Nature, Volume 171, No. 4356. April 25 1953. pp740-741. 4. Genetical Implications of the Structure of Deoxyribonucleic Acid by J.D.Watson and F.H.C.Crick. Nature, Volume 171, No. 4361. May 30 1953. pp964-967. 5. Evidence for 2-Chain Helix in Crystalline Structure of Sodium Deoxyribonucleate by Rosalind E. Franklin and R.G.Gosling. Nature, Volume 172, No. 4369, July 25 1953. pp156-157. 6. Helical Structure of Crystalline Deoxypentose Nucleic Acid, by M.H.F.Wilkins, W.E.Seeds, A.R.Stokes and H.R.Wilson. Nature, Volume 172, No. 4382, October 24 1953. pp759-762. Together these papers, announcing the discovery of DNA, provide the single most important advance in biology since Darwin's theories. Although Crick and Watson are the best known of the scientists working on the structure of deoxyribose nucleic acid (DNA) it was a collaborative venture and it is now recognised that the model used by Watson and Crick was based almost completely on the findings of Rosalind Franklin and Maurice Wilkins.
More images[The six milestone papers on the structure of DNA in original wrappers:] 1. WATSON, J. D. & CRICK, F. H. C. Molecular Structure of Nucleic Acids: A Structure for Deoxyribose Nucleic Acid; 2. WILKINS, M. H. F., STOKES, A. R. & WILSON, H. R. Molecular Structure of Deoxypentose Nucleic Acids; 3. FRANKLIN, R. E. & GOSLING, R. G. Molecular Configuration in Sodium Thymonucleate, pp. 737-41 in Nature, Vol. 171, No. 4356, April 25, 1953. 4. WATSON, J. D. & CRICK, F. H. C. Genetical Implications of the Structure of Deoxyribonucleic Acid, pp. 964-7 in Nature, Vol. 171, No. 4361, May 30, 1953. 5. FRANKLIN, R. E. & GOSLING, R. G. Evidence for 2-Chain Helix in Crystalline Structure of Sodium Deoxyribonucleate, pp. 156-7 in Nature, Vol. 172, No. 4369, July 25, 1953. 6. WILKINS, M. H. F., SEEDS, W. E. STOKES, A. R. & WILSON, H. R. Helical Structure of Crystalline Deoxypentose Nucleic Acid, pp. 759-62 in Nature, Vol. 172, No. 4382, October 24, 1953
WATSON; CRICK; WILKINS; STOKES; WILSON; FRANKLIN; GOSLING; SEEDS
Published by Macmillan, London 1953
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A VERY FINE SET OF THE DNA PAPERS. First edition, in the form in which they first appeared, of six crucial papers documenting the discovery of the structure of DNA and the mechanism of the genetic code. The first is Watson & Crick's paper 'Molecular Structure of Nucleic Acids: A Structure for Deoxyribose Nucleic Acid', which "re…cords the discovery of the molecular structure of deoxyribonucleic acid (DNA), the main component of chromosomes and the material that transfers genetic characteristics in all life forms. Publication of this paper initiated the science of molecular biology. Forty years after Watson and Crick's discovery, so much of the basic understanding of medicine and disease has advanced to the molecular level that their paper may be considered the most significant single contribution to biology and medicine in the twentieth century" (One Hundred Books Famous in Medicine, p. 362). Watson & Crick's paper is here accompanied by their paper published one month later, 'Genetical Implications of the Structure of Deoxyribonucleic Acid,' "in which they elaborated on their proposed DNA replication mechanism" (ibid.), together with one of the papers which provided the experimental data confirming their proposed structure, a follow up to 'Molecular Structure of Deoxypentose Nucleic Acids' by Wilkins et al. Also included is the 1961 paper 'General Nature of the Genetic Code for Proteins,' documenting Crick's team's efforts to crack the genetic code, amassing evidence suggesting that "the amino-acid sequence along the polypeptide chain of a protein is determined by the sequence of the bases along some particular part of the nucleic acid of the genetic material" (p. 1227), and that each acid was most likely coded by a group of three bases. In 1962, Watson, Crick, and Wilkins shared the Nobel Prize in Physiology or Medicine "for their discoveries concerning the molecular structure of nucleic acids and its significance for information transfer in living material." The first three papers were issued together in offprint from, but the journal issue offered here preceded the offprint and is actually rarer on the market. DNA was first isolated by the Swiss physician Friedrich Miescher in 1869, and over the succeeding years many researchers investigated its structure and function, with some arguing that it may be involved in genetic inheritance. By the early 1950s this had become one of the most important questions in biology. Maurice Wilkins of King's College London and his colleague Rosalind Franklin were both working on DNA, with Franklin producing X-ray diffraction images of its structure. Wilkins also introduced his friend Francis Crick to the subject, and Crick and his partner James Watson began their own investigation at the Cavendish Laboratory in Cambridge, focusing on building molecular models. After one failed attempt in which they postulated a triple-helix structure, they were banned by the Cavendish from spending any additional time on the subject. But a year later, after seeing new X-ray diffraction images taken by Franklin (notably the famous 'Photo 51', which is reproduced in the third offered paper), they resumed their work and soon announced that not only had they discovered the double-helix structure of DNA, but even more importantly, that "the specific pairing we have postulated immediately suggests a possible copying mechanism for the genetic material." When Watson and Crick's paper was submitted for publication in Nature, Sir Lawrence Bragg, the director of the Cavendish Laboratory at Cambridge, and Sir John Randall of King's College agreed that the paper should be published simultaneously with those of two other groups of researches who had also prepared important papers on DNA: Maurice Wilkins, A.R. Stokes, and H.R. Wilson, authors of 'Molecular Structure of Deoxypentose Nucleic Acids,' and Rosalind Franklin and Raymond Gosling, who submitted the paper 'Molecular Configuration in Sodium Thymonucleate.' The three papers were published in Nature under the general title 'The Molecular Structure of Nucleic Acids.' "Five weeks after Watson's and Crick's first paper in Nature, their second appeared, in which, after explaining the structure and the evidence all over again, they pursued some of the genetical implications. These flowed from the most novel, most fundamental fact of the model: "Any sequence of the pairs of the bases can fit into the structure. It follows that in a long molecule many different permutations are possible, and it therefore seems likely that the precise sequence of the bases is the code which carries the genetical information. If the actual order of the bases on one of the pair of chains were given, one could write down the exact order of the bases on the other one, because of the specific pairing." This immediately suggested, they said, how DNA duplicated itself. "Previous discussions of self-duplication have usually involved the concept of a template, or mould. Either the template was supposed to copy itself directly or it was to produce a "negative", which in its turn was to act as a template and produce the original "positive" once again. In no case has it been explained in detail how it would do this in terms of atoms and molecules." The elucidation of the structure of DNA called for a new kind of functional explanation. "Now our model for deoxyribonucleic acid is, in effect, a pair of templates, each of which is complementary to the other. We imagine that prior to duplication the hydrogen bonds [connecting the bases in pairs] are broken, and the two chains unwind and separate. Each chain then acts as a template for the formation on to itself of a new companion chain, so that eventually we shall have two pairs of chains, where we only had one before. Moreover, the sequence of the pairs of bases will have been duplicated exactly." Yet perhaps not always exactly: the model, or rather the mistake whose correction by Donohue had cleared the way for the m.
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Nature 1953. 8vo. 2 vols. Contemporary red morocco backed buckram, gilt lettering to spine; vols 171 and 172 of the journal Nature, covering 1953; diagrams and illustrations; very good.First editions of the first papers on the ground-breaking discovery of the structure of DNA, comprising: "Molecular Structure of Nucleic Acids: A… Structure for Deoxyribose Nucleic Acid", in Nature Vol.171, No. 4356, pp.737-738, 25th April, 1953 [and] Wilkins, Maurice H.F., A.R. Stokes and H.R. Wilson. "Molecular Structure of Deoxypentose Nucleic Acids", in Nature Vol.171, No. 4356, pp.738-740, 25th April, 1953 [and] Franklin (Rosalind E.) and R.G. Gosling. "Molecular Configuration in Sodium Thymonucleate", in Nature Vol.171, No. 4356, pp.740-741, 25th April, 1953 [and] Watson (James D.) & Francis Crick. "Genetic Implications of the Structure of Deoxyribonucleic Acid", in Nature Vol.171, No. 4361, pp.964-967, 30th May, 1953 [and] Wilkins (M. H. F.), W. E. Seeds, A. R. Stokes and H. R. Wilson. "Helical Structure of Crystalline Deoxypentose Nucleic Acid", in Nature, vol.172, No. 4382, pp.759-762, 24th October, 1953.These papers record the greatest biological advance of the twentieth century, a discovery which won Crick, Watson and Wilkins the Nobel Prize.

1962 Nobel Prize-Winning Scientists Signed Photograph. [James D. Watson, Francis Crick and Maurice Wilkins Signed Photograph].
Crick, Francis; James D. Watson; Maurice Wilkins; Max Ferdinand Perutz; John Kendrew
- First Edition
- Signed
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Contact seller5-star sellerOriginal photograph from the 1962 Nobel Prize Ceremony signed by Francis Crick, James Watson, and Maurice Wilkins (jointly awarded the 1962 Nobel Prize in Physiology and Medicine) as well as Max Ferdinand Perutz and John Kendrew (jointly awarded the 1962 Nobel Prize in Chemistry). Also captured in the photograph is John Steinbec…k, who was awarded the 1962 Nobel Prize in Literature. In fine condition. The Nobel Prize in Physiology or Medicine 1962 was awarded jointly to Francis Harry Compton Crick, James Dewey Watson and Maurice Hugh Frederick Wilkins "for their discoveries concerning the molecular structure of nucleic acids and its significance for information transfer in living material." In 1968, Watson published The Double Helix: A Personal Account of the Discovery of the Structure of DNA, his account of his codiscovery (along with Francis Crick) of the structure of DNA. To preserve the "real" story for the world, James Watson attempted to record his first impressions as soon after the events of 1951-1953 as possible, with all their unpleasant realities and "spirit of adventure" intact. "He has described admirably how it feels to have that frightening and beautiful experience of making a great scientific discovery" (Richard Feynman, winner of the 1965 Nobel Prize for Physics).
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Seller: Michael R. Thompson Books, A.B.A.A., Los Angeles, CA, U.S.A.Michael R. Thompson Books, A.B.A.A.
Contact seller1-star sellerThis long, heavily illustrated article, takes up more than a third of this issue of the periodical. Of particular interest is Part III, subtitled "Seven Giants Who Led the Way." It profiles Anton van Leeuwenhoek, Charles Darwin, Gregor Mendel, Louis Pasteur, Thomas Hunt Morgan, and James Watson and Francis Crick. Watson and Cric…k have both signed the section of the article that is about them. Original printed wrappers, chipped at spine. Rubberstamp of Francis H.C. Crick at the Salk Institute on front cover. This issue was given by Crick to an employee at the Salk.