D T Max (Over 4,000 results)

Hardcover. Condition: Very Good.

Hardcover. Condition: Very Good.

Hardcover. Condition: New.

Condition: good. May show signs of wear, highlighting, writing, and previous use. This item may be a former library book with typical markings. No guarantee on products that contain supplements Your satisfaction is 100% guaranteed. Twenty-five year bookseller with shipments to over fifty million happy customers.…

Paperback. Condition: Good. For two hundred years a noble Venetian family has suffered from an inherited disease that strikes their members in middle age, stealing their sleep, eating holes in their brains, and ending their lives in a matter of months. In Papua New Guinea, a primitive tribe is nearly obliterated by a sickness whose chief symptom is uncontrollable laughter. Across Europe, millions of sheep rub their fleeces raw before collapsing. In England, cows attack their owners in the milking parlors, while in the American West, thousands of deer starve to death in fields full of grass. What these strange conditions-including fatal familial insomnia, kuru, scrapie, and mad cow disease-share is their cause: prions. Prions are ordinary proteins that sometimes go wrong, resulting in neurological illnesses that are always fatal. Even more mysterious and frightening, prions are almost impossible to destroy because they are not alive and have no DNA-and the diseases they bring are now spreading around the world. In The Family That Couldn''t Sleep, essayist and journalist D. T. Max tells the spellbinding story of the prion''s hidden past and deadly future. Through exclusive interviews and original archival research, Max explains this story''s connection to human greed and ambition-from the Prussian chemist Justus von Liebig, who made cattle meatier by feeding them the flesh of other cows, to New Guinean natives whose custom of eating the brains of the dead nearly wiped them out. The biologists who have investigated these afflictions are just as extraordinary-for example, Daniel Carleton Gajdusek, a self-described "pedagogic pedophiliac pediatrician" who cracked kuru and won the Nobel Prize, and another Nobel winner, Stanley Prusiner, a driven, feared self-promoter who identified the key protein that revolutionized prion study. With remarkable precision, grace, and sympathy, Max-who himself suffers from an inherited neurological illness-explores maladies that have tormented humanity for centuries and gives reason to hope that someday cures will be found. And he eloquently demonstrates that in our relationship to nature and these ailments, we have been our own worst enemy. Advance praise "The Family that Couldn''t Sleep is a riveting detective story that plumbs one of the deepest mysteries of biology. The story takes the reader from the torments of an Italian family cursed with sleeplessness to the mad cows of England (and, now, America), following an unlikely trail of misfolded proteins. D. T. Max unfolds his absorbing narrative with rare grace and makes the science sing." -Michael Pollan, author of The Omnivore''s Dilemma and The Botany of Desire "Much has been written about prions and Mad Cow Disease-nearly all of it is worthless. Thankfully, from the world of journalism comes D.T. Max to set things right. Throw all those other "Mad Cow" books in the trash: This is the book to read about prions-or whatever you want to call them. It''s a riveting tale, told by someone with a very special understanding, derived in part from his own strange ailment. Find a cozy spot, clear your schedule and dive in." - Laurie Garrett, author of Betrayal of Trust and The Coming Plague "D. T. Max deftly unfolds the mysterious prion in all its villainous guises. Although scientists do not fully understand these proteins-how they replicate and wreak such havoc in their victims'' brains-The Family That Couldn''t Sleep reveals their historical, cultural, and scientific place in our world. Prepare to be enlightened, entertained, and frightened." -Katrina Firlik, MD, author of Another Day in the Frontal Lobe "A great book. D.T. Max has drawn the curtain on a cabinet of folly  and malady that will stagger your imagination."- Philip Weiss, author of American Taboo "D.T. Max has combined the enthralling medical anthropology of Oliver Sacks with the gothic horror of Stephen King to produce a medical detective story that is as intelligent as it is spooky. The villain of The Family That Couldn''t Sleep is the prion, a tiny little protein that causes some of the most terrifying, brain-mangling, creepy diseases known to man. Always fascinating-how could it not be, given that its characters include cannibals, mad cows, madder sheep, a Nobel prize-winning pedophile, and, most poignantly, an Italian family cursed by fatal insomnia?-Max''s book is also a gripping account of scientific discovery, and a heartfelt meditation on what it means to be cursed with an incurable, and brutal, illness." - David Plotz, author of The Genius Factory.…

Hardback. Condition: Very Good. "Brazenly entertaining. . . . It summons to the page a Broadway voice like no other."--Los Angeles Times "[An] erudite and affably self-conscious memoir of the creative process."--Vulture An intimate portrait of a genius: the late Stephen Sondheim in a series of illuminating and deeply personal interviews from the last years of his life--conversations that show the composer-lyricist as he has likely never been seen before. In 2017, New Yorker staff writer D.T. Max began working on a major profile of Stephen Sondheim that would be timed to the eventual premiere of a new musical Sondheim was writing. Sadly , that process - and the years of conversation - was cut short by Sondheim's own hesitations, then the global pandemic, and finally by the great artist's death in November 2021. Now, Max has taken the raw version of these conversations and knit them together into an unforgettable work of literature and celebration. Finale reveals Sondheim--a star who disliked the spotlight--at his most relaxed, thoughtful, sardonic, and engaging, as he talks about work, music, movies, family, New York City, aging, the creative process, and much more. Max brings you into the room and gives you a front row seat for their unusual and intimate three-year-long "pas de deux." The two bond, spar, separate, and reunite, as Max elicits from Sondheim a candor and vulnerability he seldom displayed in public.  This is a unique portrait of an artist in his twilight, offering remarkable insight into the mind and heart of a genius whose work changed American musical theater and popular culture forever.…

Hardback. Condition: Good. "Brazenly entertaining. . . . It summons to the page a Broadway voice like no other."--Los Angeles Times "[An] erudite and affably self-conscious memoir of the creative process."--Vulture An intimate portrait of a genius: the late Stephen Sondheim in a series of illuminating and deeply personal interviews from the last years of his life--conversations that show the composer-lyricist as he has likely never been seen before. In 2017, New Yorker staff writer D.T. Max began working on a major profile of Stephen Sondheim that would be timed to the eventual premiere of a new musical Sondheim was writing. Sadly , that process - and the years of conversation - was cut short by Sondheim's own hesitations, then the global pandemic, and finally by the great artist's death in November 2021. Now, Max has taken the raw version of these conversations and knit them together into an unforgettable work of literature and celebration. Finale reveals Sondheim--a star who disliked the spotlight--at his most relaxed, thoughtful, sardonic, and engaging, as he talks about work, music, movies, family, New York City, aging, the creative process, and much more. Max brings you into the room and gives you a front row seat for their unusual and intimate three-year-long "pas de deux." The two bond, spar, separate, and reunite, as Max elicits from Sondheim a candor and vulnerability he seldom displayed in public.  This is a unique portrait of an artist in his twilight, offering remarkable insight into the mind and heart of a genius whose work changed American musical theater and popular culture forever.…

Condition: Good. Pages intact with minimal writing/highlighting. The binding may be loose and creased. Dust jackets/supplements are not included. Stock photo provided. Product includes identifying sticker. Better World Books: Buy Books. Do Good.

Condition: Very Good. Former library copy. Pages intact with possible writing/highlighting. Binding strong with minor wear. Dust jackets/supplements may not be included. Includes library markings. Stock photo provided. Product includes identifying sticker. Better World Books: Buy Books. Do Good.

Condition: Good. Former library copy. Pages intact with minimal writing/highlighting. The binding may be loose and creased. Dust jackets/supplements are not included. Includes library markings. Stock photo provided. Product includes identifying sticker. Better World Books: Buy Books. Do Good.

Condition: very_good. Book is in very good condition and has little to no writing, underlining, and or highlighting. Cover may have some cosmetic wear.

Condition: very_good. Book is in very good condition and may include minimal underlining highlighting. The book can also include "From the library of" labels. May not contain miscellaneous items toys, dvds, etc. . We offer 100% money back guarantee and 24 7 customer service.

Condition: very_good. Fast Free Shipping â" Very Good condition book with a firm cover and clean pages. Shows normal use and some light wear or limited notes markings. A solid, nice copy to enjoy.

Condition: good. Book is in good condition and may include underlining highlighting and minimal wear. The book can also include "From the library of" labels. May not contain miscellaneous items toys, dvds, etc. . We offer 100% money back guarantee and 24 7 customer service.

Paperback. Condition: Fair. Reprint. The item might be beaten up but readable. May contain markings or highlighting, as well as stains, bent corners, or any other major defect, but the text is not obscured in any way.

Hardcover. Condition: Very Good. No Jacket. May have limited writing in cover pages. Pages are unmarked. ~ ThriftBooks: Read More, Spend Less.

Hardcover. Condition: Very Good. No Jacket. May have limited writing in cover pages. Pages are unmarked. ~ ThriftBooks: Read More, Spend Less.

Hardcover. Condition: As New. No Jacket. Pages are clean and are not marred by notes or folds of any kind. ~ ThriftBooks: Read More, Spend Less.

Hardcover. Condition: Very Good. No Jacket. Former library book; May have limited writing in cover pages. Pages are unmarked. ~ ThriftBooks: Read More, Spend Less.

Hardcover. Condition: Very Good. No Jacket. Former library book; May have limited writing in cover pages. Pages are unmarked. ~ ThriftBooks: Read More, Spend Less.

Hardcover. Condition: Very Good. No Jacket. Former library book; May have limited writing in cover pages. Pages are unmarked. ~ ThriftBooks: Read More, Spend Less.

Hardcover. Condition: Very Good. No Jacket. Former library book; May have limited writing in cover pages. Pages are unmarked. ~ ThriftBooks: Read More, Spend Less.

Hardcover. Condition: Very Good. No Jacket. May have limited writing in cover pages. Pages are unmarked. ~ ThriftBooks: Read More, Spend Less.

Condition: very_good.

Condition: good. Gently used with minimal wear on the corners and cover. A few pages may contain light highlighting or writing, but the text remains fully legible. Dust jacket may be missing, and supplemental materials like CDs or codes may not be included. May be ex-library with library markings. Ships promptly. …

Condition: New. Ebbeler, Jeffrey (illustrator).

Paperback. Condition: Good. For two hundred years a noble Venetian family has suffered from an inherited disease that strikes their members in middle age, stealing their sleep, eating holes in their brains, and ending their lives in a matter of months. In Papua New Guinea, a primitive tribe is nearly obliterated by a sickness whose chief symptom is uncontrollable laughter. Across Europe, millions of sheep rub their fleeces raw before collapsing. In England, cows attack their owners in the milking parlors, while in the American West, thousands of deer starve to death in fields full of grass. What these strange conditions-including fatal familial insomnia, kuru, scrapie, and mad cow disease-share is their cause: prions. Prions are ordinary proteins that sometimes go wrong, resulting in neurological illnesses that are always fatal. Even more mysterious and frightening, prions are almost impossible to destroy because they are not alive and have no DNA-and the diseases they bring are now spreading around the world. In The Family That Couldn''t Sleep, essayist and journalist D. T. Max tells the spellbinding story of the prion''s hidden past and deadly future. Through exclusive interviews and original archival research, Max explains this story''s connection to human greed and ambition-from the Prussian chemist Justus von Liebig, who made cattle meatier by feeding them the flesh of other cows, to New Guinean natives whose custom of eating the brains of the dead nearly wiped them out. The biologists who have investigated these afflictions are just as extraordinary-for example, Daniel Carleton Gajdusek, a self-described "pedagogic pedophiliac pediatrician" who cracked kuru and won the Nobel Prize, and another Nobel winner, Stanley Prusiner, a driven, feared self-promoter who identified the key protein that revolutionized prion study. With remarkable precision, grace, and sympathy, Max-who himself suffers from an inherited neurological illness-explores maladies that have tormented humanity for centuries and gives reason to hope that someday cures will be found. And he eloquently demonstrates that in our relationship to nature and these ailments, we have been our own worst enemy. Advance praise "The Family that Couldn''t Sleep is a riveting detective story that plumbs one of the deepest mysteries of biology. The story takes the reader from the torments of an Italian family cursed with sleeplessness to the mad cows of England (and, now, America), following an unlikely trail of misfolded proteins. D. T. Max unfolds his absorbing narrative with rare grace and makes the science sing." -Michael Pollan, author of The Omnivore''s Dilemma and The Botany of Desire "Much has been written about prions and Mad Cow Disease-nearly all of it is worthless. Thankfully, from the world of journalism comes D.T. Max to set things right. Throw all those other "Mad Cow" books in the trash: This is the book to read about prions-or whatever you want to call them. It''s a riveting tale, told by someone with a very special understanding, derived in part from his own strange ailment. Find a cozy spot, clear your schedule and dive in." - Laurie Garrett, author of Betrayal of Trust and The Coming Plague "D. T. Max deftly unfolds the mysterious prion in all its villainous guises. Although scientists do not fully understand these proteins-how they replicate and wreak such havoc in their victims'' brains-The Family That Couldn''t Sleep reveals their historical, cultural, and scientific place in our world. Prepare to be enlightened, entertained, and frightened." -Katrina Firlik, MD, author of Another Day in the Frontal Lobe "A great book. D.T. Max has drawn the curtain on a cabinet of folly  and malady that will stagger your imagination."- Philip Weiss, author of American Taboo "D.T. Max has combined the enthralling medical anthropology of Oliver Sacks with the gothic horror of Stephen King to produce a medical detective story that is as intelligent as it is spooky. The villain of The Family That Couldn''t Sleep is the prion, a tiny little protein that causes some of the most terrifying, brain-mangling, creepy diseases known to man. Always fascinating-how could it not be, given that its characters include cannibals, mad cows, madder sheep, a Nobel prize-winning pedophile, and, most poignantly, an Italian family cursed by fatal insomnia?-Max''s book is also a gripping account of scientific discovery, and a heartfelt meditation on what it means to be cursed with an incurable, and brutal, illness." - David Plotz, author of The Genius Factory.…

hardcover. Condition: Very Good. Connecting readers with great books since 1972! Used books may not include companion materials, and may have some shelf wear or limited writing. We ship orders daily and Customer Service is our top priority.

hardcover. Condition: Very Good. Connecting readers with great books since 1972! Used books may not include companion materials, and may have some shelf wear or limited writing. We ship orders daily and Customer Service is our top priority.

hardcover. Condition: Very Good. Connecting readers with great books since 1972! Used books may not include companion materials, and may have some shelf wear or limited writing. We ship orders daily and Customer Service is our top priority.