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Published by Plenum Press, New York, 1971
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Language: English
Published by Plenum Publishing Corporation, 1977
ISBN 10: 0306310376 ISBN 13: 9780306310379
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Language: English
Published by Plenum Press, London, 1975
ISBN 10: 0306360039 ISBN 13: 9780306360039
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Language: English
Published by Plenum Press, London, 1974
ISBN 10: 0306360020 ISBN 13: 9780306360022
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Taschenbuch. Condition: Neu. Druck auf Anfrage Neuware - Printed after ordering - On picking up this first volume of a new series of books the reader may ask the two questions: (a) why research methods and (b) why in neurochem istry The answers to these questions are easy - they more than justify the volumes to come and show the strong need for their existence. It is customary to think of methods as a necessary but unexciting means to an end - to relegate advances in methodology to a minor role in the creative, original portion of advances in science. This is not the case; the pace-setting function of methodology is well illustrated in most areas of neurobiology. To formulate our questions to Nature (which is the essence of experimental design), methodology is needed; to get answers to our ques tions we have to devise yet new methods. The chapters of the present volume fully illustrate how the development of a new method can cut a new path how it can open new fields, just as the microscope founded histology. Heter ogeneity of structures presents a formidable challenge for methodology in the nervous system, yet methods for separating the structures are essential if we ever want to decipher the enigma of functional contribution of the ele ments to the whole. The problem is not only physical separation-clearly methods are essential to study complex structures in situ.
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Taschenbuch. Condition: Neu. Research Methods in Neurochemistry | Volume 4 | Neville Marks | Taschenbuch | xx | Englisch | 2012 | Humana | EAN 9781461577560 | Verantwortliche Person für die EU: Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg, juergen[dot]hartmann[at]springer[dot]com | Anbieter: preigu.
Taschenbuch. Condition: Neu. Research Methods in Neurochemistry | Volume 2 | Neville Marks | Taschenbuch | xviii | Englisch | 2012 | Springer | EAN 9781461577539 | Verantwortliche Person für die EU: Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg, juergen[dot]hartmann[at]springer[dot]com | Anbieter: preigu.
Taschenbuch. Condition: Neu. Research Methods in Neurochemistry | Volume 3 | Neville Marks | Taschenbuch | xx | Englisch | 2011 | Springer | EAN 9781461344605 | Verantwortliche Person für die EU: Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg, juergen[dot]hartmann[at]springer[dot]com | Anbieter: preigu.
Taschenbuch. Condition: Neu. Research Methods in Neurochemistry | Volume 1 | Neville Marks | Taschenbuch | xxii | Englisch | 2012 | Springer US | EAN 9781461577508 | Verantwortliche Person für die EU: Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg, juergen[dot]hartmann[at]springer[dot]com | Anbieter: preigu.
Taschenbuch. Condition: Neu. Research Methods in Neurochemistry | Volume 5 | Neville Marks (u. a.) | Taschenbuch | xvi | Englisch | 2013 | Springer | EAN 9781461577591 | Verantwortliche Person für die EU: Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg, juergen[dot]hartmann[at]springer[dot]com | Anbieter: preigu.
Taschenbuch. Condition: Neu. Druck auf Anfrage Neuware - Printed after ordering - The fourth volume of Research Methods in Neurochemistry includes chapters on different aspects of topics touched on in previous volumes and develops a number of new themes as well. The bias, though not entirely intended, is directed toward studies of macromolecules, both at the meta bolic level in relation to protein synthesis and at the structural level in rela tion to specific proteins and lipids. The new departures concern subjects in Section I with marked applied bias: biochemical studies of nervous system tumors and of the cerebrospinal fluid, both of which we hope will be of value to clinical as well as basic scientists. Biogenic amines and the enzymes involved in their metabolism figure again in Section II, where the powerful tool of mass spectrometry receives further treatment in relation to the analysis of dansyl derivatives of trace amines in the brain. Once again we remain grateful to the individual authors, both for their contributions and patience, and to Plenum Press for their continued interest and cooperation. Thanks are also due to colleagues and friends for their comments and criticisms on the series as a whole; suggestions for future volumes will always be welcome and should be sent to one of the editors. Richard Rodnight, London Neville Marks, New York March 1978 ix Contents Section I PROPERTIES OF INTACT NEURAL TISSUES Chapter 1 Biochemical Study of Tumors of the Nervous System. . . . . . . . . . . . . . . . 3 Norman Allen I. Introduction. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 3 II. Human Brain Tumors. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 7 A. Autopsy Specimens. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Taschenbuch. Condition: Neu. Druck auf Anfrage Neuware - Printed after ordering - This second volume of Research Methods in Neurochemistry develops themes featured in the first volume and also introduces new approaches to neurochemical methodology. A further chapter on cell separation tech niques seemed justified in view of its general importance to the study of neurone-glia relationships and the complexity of the methodological prob lems involved. Biogenic amines also receive more attention in chapters on the assay of monoamine oxidase, catechol-o-methyltransferase and pineal indoles; subcellular fractionation features again in chapters on methods for the isolation and study of brain mitochondria and synaptic vesicles. Among the new subjects dealt with in this volume, the chapter on cell culture per haps represents the most distinctive departure from the themes of the first volume. Culture of neural tissue and cells has, of course, been studied by neurobiologists for several decades, but it is only recently that the neuro chemical potential of this approach has begun to be exploited. We believe that neurochemists wishing to enter this field will find Dr. Herschman's extensive treatment of the subject in this volume of particular interest. Readers familiar with Volume 1 will note that the balance of subjects in this volume is broadly similar. Thus it has proved convenient to group the chapters under the same section headings as before, with the inclusion of chapters on amino acids in Section IV.