Language: English
Published by Institute of Physics Publishing, 2023
ISBN 10: 0750358408 ISBN 13: 9780750358408
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hardcover. Condition: Fine.
Language: English
Published by Institute of Physics Publishing, 2023
ISBN 10: 0750358408 ISBN 13: 9780750358408
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Language: English
Published by John Wiley & Sons Inc, New York, 2023
ISBN 10: 1394209215 ISBN 13: 9781394209217
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Hardcover. Condition: new. Hardcover. MULTI-DRUG RESISTANCE IN CANCER The book details the mechanisms underlying multi-drug cellular resistance and the targets of novel chemotherapeutic agents. Cancer is a major killer all over the world. Even with all the progress made, chemotherapy is still the mainstay of modern cancer treatment. The progression of the cellular defeat of numerous independent anticancer drugs in terms of their chemical structure is a major barrier to successful chemotherapy. Multi-drug resistance (MDR) is a term for the fact that most cancer patients exhibit this phenomenon. According to the numbers, drug resistance carries the blame for 90% of cancer patient deaths. Refractory cancer and tumor recurrence are common outcomes of prolonged chemotherapy. Because of the prevalence of drug-resistance mutations, the difficulty of treating tumors increases and the therapeutic efficacy of drugs decreases. Multi-Drug Resistance in Cancer: Mechanism and Treatment Strategies contains nine chapters that cover topics such as: studying the mechanics of resistance to drugs by autophagy; studies to delineate the role of efflux transporters; expression of drug transporters; resistance to targeted therapies in breast cancer; advances in metallodrug driven combination treatment for cancer; and use of natural agents for the overcoming of cancer drug resistance. The book aims to provide the latest data on the mechanisms of cellular resistance to anticancer agents currently used in clinical treatment. It provides a better understanding of the mechanisms of MDR and targets of novel chemotherapy agents which should guide future research concerning new effective strategies in cancer treatment. Audience This book is written for pharmaceutical and biomedical scientists and researchers at both the bench and in the clinic who are interested in the mechanisms and strategies for overcoming cancers multi-drug resistance. Shipping may be from multiple locations in the US or from the UK, depending on stock availability.
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Language: English
Published by Apple Academic Press, 2024
ISBN 10: 1774916789 ISBN 13: 9781774916780
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Language: English
Published by Apple Academic Press, 2024
ISBN 10: 1774916789 ISBN 13: 9781774916780
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