Language: French
Published by Editions Notre Savoir, 2021
ISBN 10: 6202869380 ISBN 13: 9786202869386
Seller: Lucky's Textbooks, Dallas, TX, U.S.A.
Condition: New.
Language: Portuguese
Published by Edições Nosso Conhecimento, 2021
ISBN 10: 6202869402 ISBN 13: 9786202869409
Seller: Lucky's Textbooks, Dallas, TX, U.S.A.
Condition: New.
Language: Polish
Published by Wydawnictwo Nasza Wiedza, 2021
ISBN 10: 6202869453 ISBN 13: 9786202869454
Seller: Lucky's Textbooks, Dallas, TX, U.S.A.
Condition: New.
Language: French
Published by Editions Notre Savoir, 2021
ISBN 10: 6202869380 ISBN 13: 9786202869386
Seller: Ria Christie Collections, Uxbridge, United Kingdom
US$ 31.48
Quantity: Over 20 available
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Language: French
Published by Editions Notre Savoir 2021-09-08, 2021
ISBN 10: 6202869380 ISBN 13: 9786202869386
Seller: Chiron Media, Wallingford, United Kingdom
US$ 28.89
Quantity: 10 available
Add to basketPaperback. Condition: New.
Language: English
Published by VDM Verlag Dr. Mueller Aktiengesellschaft & Co. KG, 2014
ISBN 10: 3659518069 ISBN 13: 9783659518065
Seller: Books Puddle, New York, NY, U.S.A.
Condition: New. pp. 80.
Seller: Ria Christie Collections, Uxbridge, United Kingdom
US$ 31.48
Quantity: Over 20 available
Add to basketCondition: New. In.
Seller: Ria Christie Collections, Uxbridge, United Kingdom
US$ 31.48
Quantity: Over 20 available
Add to basketCondition: New. In.
Language: Portuguese
Published by Edições Nosso Conhecimento, 2021
ISBN 10: 6202869402 ISBN 13: 9786202869409
Seller: Ria Christie Collections, Uxbridge, United Kingdom
US$ 31.48
Quantity: Over 20 available
Add to basketCondition: New. In.
Language: Polish
Published by Wydawnictwo Nasza Wiedza, 2021
ISBN 10: 6202869453 ISBN 13: 9786202869454
Seller: Ria Christie Collections, Uxbridge, United Kingdom
US$ 31.76
Quantity: Over 20 available
Add to basketCondition: New. In.
Language: Portuguese
Published by Edi�oes Nosso Conhecimento 2021-09-08, 2021
ISBN 10: 6202869402 ISBN 13: 9786202869409
Seller: Chiron Media, Wallingford, United Kingdom
US$ 28.89
Quantity: 10 available
Add to basketPaperback. Condition: New.
Language: Polish
Published by Wydawnictwo Nasza Wiedza 2021-09-09, 2021
ISBN 10: 6202869453 ISBN 13: 9786202869454
Seller: Chiron Media, Wallingford, United Kingdom
US$ 28.89
Quantity: 10 available
Add to basketPaperback. Condition: New.
Language: German
Published by Verlag Unser Wissen 2021-09-08, 2021
ISBN 10: 6202869372 ISBN 13: 9786202869379
Seller: Chiron Media, Wallingford, United Kingdom
US$ 28.93
Quantity: 10 available
Add to basketPaperback. Condition: New.
Language: English
Published by LAP LAMBERT Academic Publishing, 2013
ISBN 10: 3659368725 ISBN 13: 9783659368721
Seller: moluna, Greven, Germany
Condition: New.
Language: English
Published by LAP LAMBERT Academic Publishing Feb 2011, 2011
ISBN 10: 3844311173 ISBN 13: 9783844311174
Seller: buchversandmimpf2000, Emtmannsberg, BAYE, Germany
Taschenbuch. Condition: Neu. Neuware -The epidermal growth factor receptor (EGFR) is under investigation as a therapeutic target for cancers. Colon cancer cell lines are variably dependent on autocrine stimulation of EGFR. This book therefore,examines the effects of a selective EGFR tyrosine kinase inhibitor, Gefitinib (¿Iressa'', ZD1839), on proliferation and survival of colon cancer cell lines whose autonomous proliferation is either EGFR ligand dependent or EGFR ligand independent. Using computational approach , different structural analogues were developed for Iressa, how it inhibits the epidermal growth factor kinase ; the studies include nature of the colon cancer and how Iressa work to stop cancer and also explains the ligand binding in EGFR kinase. The consequences help to understand the nature of epidermal growth factor receptor kinase and how to inhibit intra and extra cellular signal. The In-silico properties facilitate more efficient design of screening libraries and serves as a foundation for numerous ADME compound profiling and drug ability assessments along the drug discovery value chain. It also helps to stop the cancer development; a new guideline for the design of inhibitors.Books on Demand GmbH, Überseering 33, 22297 Hamburg 76 pp. Englisch.
Language: Spanish
Published by Ediciones Nuestro Conocimiento Sep 2021, 2021
ISBN 10: 6202869399 ISBN 13: 9786202869393
Seller: buchversandmimpf2000, Emtmannsberg, BAYE, Germany
Taschenbuch. Condition: Neu. Neuware -El receptor del factor de crecimiento epidérmico (EGFR) está siendo investigado como objetivo terapéutico para los cánceres. Las líneas celulares de cáncer de colon dependen de manera variable de la estimulación autocrina del EGFR. Este libro, por lo tanto, examina los efectos de un inhibidor selectivo de la tirosina cinasa del EGFR, Gefitinib ('Iressa', ZD1839), en la proliferación y supervivencia de líneas celulares de cáncer de colon cuya proliferación autónoma depende del ligando del EGFR o es independiente del mismo. Utilizando un enfoque computacional, se desarrollaron diferentes análogos estructurales para Iressa, cómo inhibe el factor de crecimiento epidérmico quinasa; los estudios incluyen la naturaleza del cáncer de colon y cómo Iressa trabaja para detener el cáncer y también explica la unión del ligando en la quinasa EGFR. Las consecuencias ayudan a entender la naturaleza del receptor del factor de crecimiento epidérmico cinasa y cómo inhibir la señal intra y extra celular. Las propiedades In-silico facilitan un diseño más eficiente de las bibliotecas de detección y sirven de base para numerosos perfiles de compuestos ADME y evaluaciones de la capacidad de los fármacos a lo largo de la cadena de valor del descubrimiento de fármacos. También ayuda a detener el desarrollo del cáncer; una nueva directriz para el diseño de inhibidores.Books on Demand GmbH, Überseering 33, 22297 Hamburg 76 pp. Spanisch.
Language: English
Published by LAP LAMBERT Academic Publishing, 2014
ISBN 10: 3659518069 ISBN 13: 9783659518065
Seller: Mispah books, Redhill, SURRE, United Kingdom
US$ 114.72
Quantity: 1 available
Add to basketPaperback. Condition: Like New. LIKE NEW. SHIPS FROM MULTIPLE LOCATIONS. book.
Language: French
Published by Editions Notre Savoir, 2021
ISBN 10: 6202869380 ISBN 13: 9786202869386
Seller: moluna, Greven, Germany
Condition: New.
Language: English
Published by LAP LAMBERT Academic Publishing, 2013
ISBN 10: 3659368725 ISBN 13: 9783659368721
Seller: Mispah books, Redhill, SURRE, United Kingdom
US$ 132.68
Quantity: 1 available
Add to basketPaperback. Condition: Like New. LIKE NEW. SHIPS FROM MULTIPLE LOCATIONS. book.
Language: French
Published by Editions Notre Savoir Sep 2021, 2021
ISBN 10: 6202869380 ISBN 13: 9786202869386
Seller: buchversandmimpf2000, Emtmannsberg, BAYE, Germany
Taschenbuch. Condition: Neu. Neuware -Le récepteur du facteur de croissance épidermique (EGFR) est à l'étude en tant que cible thérapeutique pour les cancers. Les lignées de cellules cancéreuses du côlon dépendent de manière variable de la stimulation autocrine de l'EGFR. Ce livre examine donc les effets d'un inhibiteur sélectif de la tyrosine kinase du R-EGF, le Gefitinib ('Iressa', ZD1839), sur la prolifération et la survie des lignées cellulaires de cancer du côlon dont la prolifération autonome est soit dépendante du ligand du R-EGF, soit indépendante du ligand du R-EGF. En utilisant une approche computationnelle, différents analogues structurels ont été développés pour l'Iressa, comment il inhibe le facteur de croissance épidermique kinase ; les études comprennent la nature du cancer du colon et comment l'Iressa agit pour arrêter le cancer et explique également la liaison du ligand dans l'EGFR kinase. Les conséquences aident à comprendre la nature de la kinase du récepteur du facteur de croissance épidermique et la manière d'inhiber le signal intra et extracellulaire. Les propriétés in silico facilitent une conception plus efficace des bibliothèques de criblage et servent de base à de nombreux profils de composés ADME et à l'évaluation des capacités des médicaments tout au long de la chaîne de valeur de la découverte de médicaments. Elles contribuent également à freiner le développement du cancer ; une nouvelle ligne directrice pour la conception d'inhibiteurs.VDM Verlag, Dudweiler Landstraße 99, 66123 Saarbrücken 76 pp. Französisch.
Language: Dutch
Published by Uitgeverij Onze Kennis, 2021
ISBN 10: 6202869437 ISBN 13: 9786202869430
Seller: moluna, Greven, Germany
Condition: New.
Language: French
Published by Editions Notre Savoir, 2021
ISBN 10: 6202869380 ISBN 13: 9786202869386
Seller: preigu, Osnabrück, Germany
Taschenbuch. Condition: Neu. IRESSA - Une aubaine pour le cancer du côlon | Études in-silico sur le médicament Iressa inhibant le récepteur du facteur de croissance épidermique (EGFR) impliqué dans le cancer du colon | Saprativ Das | Taschenbuch | Kartoniert / Broschiert | Französisch | 2021 | Editions Notre Savoir | EAN 9786202869386 | Verantwortliche Person für die EU: preigu GmbH & Co. KG, Lengericher Landstr. 19, 49078 Osnabrück, mail[at]preigu[dot]de | Anbieter: preigu.
Language: Dutch
Published by Uitgeverij Onze Kennis Sep 2021, 2021
ISBN 10: 6202869437 ISBN 13: 9786202869430
Seller: buchversandmimpf2000, Emtmannsberg, BAYE, Germany
Taschenbuch. Condition: Neu. Neuware -De epidermale groeifactor receptor (EGFR) wordt onderzocht als therapeutisch doelwit voor kankers. Koloniekankercellijnen zijn variabel afhankelijk van de autocriene stimulatie van de EFGR. Dit boek onderzoekt daarom de effecten van een selectieve EGFR tyrosine kinase remmer, Gefitinib ('Iressa', ZD1839), op de proliferatie en overleving van darmkankercellijnen waarvan de autonome proliferatie ofwel EGFR-ligandafhankelijk ofwel EGFR-ligandonafhankelijk is. Met behulp van computationele benadering werden verschillende structurele analogen ontwikkeld voor Iressa, hoe het de epidermale groeifactor kinase remt; de studies omvatten de aard van de darmkanker en hoe Iressa werkt om kanker te stoppen en verklaart ook de ligand binding in EGFR kinase. De gevolgen helpen om de aard van de epidermale groeifactor receptor kinase te begrijpen en hoe het intra- en extracellulaire signaal kan worden geremd. De in-silico-eigenschappen maken een efficiëntere opzet van screeningbibliotheken mogelijk en dienen als basis voor talrijke ADME compound profiling en drug ability assessments in de gehele waardeketen van de drug discovery. Het helpt ook om de ontwikkeling van kanker te stoppen; een nieuwe richtlijn voor het ontwerp van remmers.Books on Demand GmbH, Überseering 33, 22297 Hamburg 76 pp. Niederländisch.
Language: Polish
Published by Wydawnictwo Nasza Wiedza, 2021
ISBN 10: 6202869453 ISBN 13: 9786202869454
Seller: moluna, Greven, Germany
Condition: New.
Language: Portuguese
Published by Edições Nosso Conhecimento, 2021
ISBN 10: 6202869402 ISBN 13: 9786202869409
Seller: moluna, Greven, Germany
Condition: New.
Language: German
Published by Verlag Unser Wissen Sep 2021, 2021
ISBN 10: 6202869372 ISBN 13: 9786202869379
Seller: buchversandmimpf2000, Emtmannsberg, BAYE, Germany
Taschenbuch. Condition: Neu. Neuware -Der epidermale Wachstumsfaktorrezeptor (EGFR) wird derzeit als therapeutisches Ziel für Krebserkrankungen untersucht. Dickdarmkrebs-Zelllinien sind variabel abhängig von der autokrinen Stimulation des EGFR. Dieses Buch untersucht daher die Auswirkungen eines selektiven EGFR-Tyrosinkinase-Inhibitors, Gefitinib ('Iressa', ZD1839), auf die Proliferation und das Überleben von Dickdarmkrebs-Zelllinien, deren autonome Proliferation entweder EGFR-Ligand-abhängig oder EGFR-Ligand-unabhängig ist. Unter Verwendung eines rechnergestützten Ansatzes wurden verschiedene strukturelle Analoga für Iressa entwickelt, wie es die epidermale Wachstumsfaktor-Kinase hemmt; die Studien umfassen die Art des Dickdarmkrebses und die Art und Weise, wie Iressa Krebs stoppt und auch die Ligandenbindung in der EGFR-Kinase erklärt. Die Folgen helfen, die Natur der epidermalen Wachstumsfaktor-Rezeptorkinase zu verstehen und zu verstehen, wie intra- und extrazelluläre Signale gehemmt werden können. Die In-silico-Eigenschaften erleichtern ein effizienteres Design von Screening-Bibliotheken und dienen als Grundlage für zahlreiche ADME-Substanzprofilierungen und Bewertungen der Arzneimittelfähigkeit entlang der Wertschöpfungskette der Arzneimittelentdeckung. Sie hilft auch, die Krebsentwicklung zu stoppen; eine neue Richtlinie für die Entwicklung von Inhibitoren.Books on Demand GmbH, Überseering 33, 22297 Hamburg 80 pp. Deutsch.
Language: Italian
Published by Edizioni Sapienza Sep 2021, 2021
ISBN 10: 6202869410 ISBN 13: 9786202869416
Seller: buchversandmimpf2000, Emtmannsberg, BAYE, Germany
Taschenbuch. Condition: Neu. Neuware -Il recettore del fattore di crescita epidermico (EGFR) è in fase di studio come bersaglio terapeutico per i tumori. Le linee cellulari del cancro del colon dipendono in modo variabile dalla stimolazione autocrina dell'EGFR. Questo libro, pertanto, esamina gli effetti di un inibitore selettivo della tirosina chinasi EGFR, Gefitinib ('Iressa', ZD1839), sulla proliferazione e la sopravvivenza delle linee cellulari del cancro del colon la cui proliferazione autonoma è dipendente dal ligando EGFR o indipendente dal ligando EGFR. Utilizzando l'approccio computazionale, sono stati sviluppati diversi analoghi strutturali per Iressa, come inibisce il fattore di crescita chinasi epidermica; gli studi includono la natura del cancro al colon e come Iressa lavora per fermare il cancro e spiega anche il legame del ligando nella chinasi EGFR. Le conseguenze aiutano a capire la natura della chinasi del fattore di crescita epidermico e come inibire il segnale intra ed extracellulare. Le proprietà in silico facilitano la progettazione più efficiente delle biblioteche di screening e servono come base per numerosi profili di composti ADME e per la valutazione delle capacità dei farmaci lungo la catena del valore della scoperta del farmaco. Aiuta anche a fermare lo sviluppo del cancro; una nuova linea guida per la progettazione degli inibitori.Books on Demand GmbH, Überseering 33, 22297 Hamburg 76 pp. Italienisch.
Language: Portuguese
Published by Edições Nosso Conhecimento Sep 2021, 2021
ISBN 10: 6202869402 ISBN 13: 9786202869409
Seller: buchversandmimpf2000, Emtmannsberg, BAYE, Germany
Taschenbuch. Condition: Neu. Neuware -O receptor do factor de crescimento epidérmico (EGFR) está a ser investigado como alvo terapêutico para os cancros. As linhas celulares do cancro do cólon dependem variavelmente da estimulação autocrítica do EGFR. Este livro, portanto, examina os efeitos de um inibidor selectivo de tirosina quinase EGFR, Gefitinib ('Iressa', ZD1839), na proliferação e sobrevivência das linhas celulares do cancro do cólon cuja proliferação autónoma é dependente do ligante EGFR ou independente do ligante EGFR. Utilizando uma abordagem computacional, foram desenvolvidos diferentes análogos estruturais para a Iressa, como inibe a quinase do factor de crescimento epidérmico; os estudos incluem a natureza do cancro do cólon e como a Iressa trabalha para parar o cancro e também explica a ligação ligandosa na quinase EGFR. As consequências ajudam a compreender a natureza da cinase receptora do factor de crescimento epidérmico e como inibir o sinal intra e extracelular. As propriedades In-silico facilitam a concepção mais eficiente de bibliotecas de rastreio e servem de base para numerosas avaliações do perfil do composto ADME e da capacidade de fármacos ao longo da cadeia de valor da descoberta de fármacos. Também ajuda a parar o desenvolvimento do cancro; uma nova directriz para a concepção de inibidores.Books on Demand GmbH, Überseering 33, 22297 Hamburg 76 pp. Portugiesisch.